2026-04-13T15:32:59Zhttps://recercat.cat/oai/request
oai:recercat.cat:2072/4718102025-10-13T11:02:18Zcom_2072_98col_2072_378192
RECERCAT author Àvila-Cabré, Sílvia author Pérez-Trujillo, Míriam author Albiol i Sala, Joan author Ferrer, Pau 2023 Methanol is increasingly gaining attraction as renewable carbon source to produce specialty and commodity chemicals, as it can be generated from renewable sources such as carbon dioxide (CO2). In this context, native methylotrophs such as the yeast Komagataella phaffii (syn Pichia pastoris) are potentially attractive cell factories to produce a wide range of products from this highly reduced substrate. However, studies addressing the potential of this yeast to produce bulk chemicals from methanol are still scarce. 3-Hydroxypropionic acid (3-HP) is a platform chemical which can be converted into acrylic acid and other commodity chemicals and biopolymers. 3-HP can be naturally produced by several bacteria through different metabolic pathways. open access Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original. https://creativecommons.org/licenses/by/4.0/ 3-Hydroxypropionic acid Pichia pastoris Komagataella phaffii Methanol β-Alanine pathway Metabolic engineering Engineering the synthetic β-alanine pathway in Komagataella phaffii for conversion of methanol into 3-hydroxypropionic acid Article