2026-04-14T03:18:38Zhttps://recercat.cat/oai/request

oai:recercat.cat:2072/4711612025-07-29T22:11:27Zcom_2072_98col_2072_378192

Small renal masses in Latin-American population : Characteristics and prognostic factors for survival, recurrence and metastasis - A multi-institutional study from LARCG database Mourão, T.C. Abreu, Diego Carvalhal, Gustavo Franco Gueglio, Guillermo M. da Costa, Walter Henriques Calsavara, Vinicius Fernando Meza-Montoya, Luis Bengió, Rúben Guillermo Scorticati, Carlos H. Castillejos-Molina, Ricardo Alonso Rodriguez-Covarrubias, Francisco Autran Gómez, Ana María Campos-Salcedo, José Gadú Nolazco, Alejandro Ameri, Carlos Alberto Zampolli, Hamilton De Campos Langenhin, Raúl Muguruza, Diego Tobias-Machado, Marcos Mingote, Pablo Clavijo, Jorge Nogueira, Lucas Mendes Clark, Omar Rovegno, Agustín Roberto Secín, Fernando Pablo Decia, Ricardo Cardoso Guimarães, Gustavo Glina, Sidney Rodríguez Faba, Óscar Palou, Juan Zequi, Stênio de Cássio Universitat Autònoma de Barcelona Kidney cancer Latin America Nephrectomy Nephron-sparing surgery Renal cell carcinoma To evaluate demographic, clinical and pathological characteristics of small renal masses (SRM) (≤ 4 cm) in a Latin-American population provided by LARCG (Latin-American Renal Cancer Group) and analyze predictors of survival, recurrence and metastasis. A multi-institutional retrospective cohort study of 1523 patients submitted to surgical treatment for non-metastatic SRM from 1979 to 2016. Comparisons between radical (RN) or partial nephrectomy (PN) and young or elderly patients were performed. Kaplan-Meier curves and log-rank tests estimated 10-year overall survival. Predictors of local recurrence or metastasis were analyzed by a multivariable logistic regression model. PN and RN were performed in 897 (66%) and 461 (34%) patients. A proportional increase of PN cases from 48.5% (1979-2009) to 75% (after 2009) was evidenced. Stratifying by age, elderly patients (≥ 65 years) had better 10-year OS rates when submitted to PN (83.5%), than RN (54.5%), p = 0.044. This disparity was not evidenced in younger patients. On multivariable model, bilaterality, extracapsular extension and ASA (American Society of Anesthesiologists) classification ≥3 were predictors of local recurrence. We did not identify significant predictors for distant metastasis in our series. PN is performed in Latin-America in a similar proportion to developed areas and it has been increasing in the last years. Even in elderly individuals, if good functional status, sufficiently fit to surgery, and favorable tumor characteristics, they should be encouraged to perform PN. Intending to an earlier diagnosis of recurrence or distant metastasis, SRM cases with unfavorable characteristics should have a more rigorous follow-up routine. 2020 Article https://ddd.uab.cat/record/284135 urn:10.1186/s12894-020-00649-8 urn:oai:ddd.uab.cat:284135 urn:scopus_id:85087531592 urn:articleid:14712490v20n1p85 urn:pmid:32615971 urn:pmc-uid:7331283 urn:pmcid:PMC7331283 urn:oai:pubmedcentral.nih.gov:7331283 urn:oai:egreta.uab.cat:publications/8cf32968-f788-4646-ba93-3c1b3f712297 eng BMC Urology ; Vol. 20 Núm. 1 (february 2020), p. 85 open access Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original. https://creativecommons.org/licenses/by/4.0/ application/pdf