2026-04-17T00:43:47Zhttps://recercat.cat/oai/request

oai:recercat.cat:2072/4711612025-07-29T22:11:27Zcom_2072_98col_2072_378192

00925njm 22002777a 4500 dc Mourão, T.C. author Abreu, Diego author Carvalhal, Gustavo Franco author Gueglio, Guillermo M. author da Costa, Walter Henriques author Calsavara, Vinicius Fernando author Meza-Montoya, Luis author Bengió, Rúben Guillermo author Scorticati, Carlos H. author Castillejos-Molina, Ricardo Alonso author Rodriguez-Covarrubias, Francisco author Autran Gómez, Ana María author Campos-Salcedo, José Gadú author Nolazco, Alejandro author Ameri, Carlos Alberto author Zampolli, Hamilton De Campos author Langenhin, Raúl author Muguruza, Diego author Tobias-Machado, Marcos author Mingote, Pablo author Clavijo, Jorge author Nogueira, Lucas Mendes author Clark, Omar author Rovegno, Agustín Roberto author Secín, Fernando Pablo author Decia, Ricardo author Cardoso Guimarães, Gustavo author Glina, Sidney author Rodríguez Faba, Óscar author Palou, Juan author Zequi, Stênio de Cássio author Universitat Autònoma de Barcelona author 2020 To evaluate demographic, clinical and pathological characteristics of small renal masses (SRM) (≤ 4 cm) in a Latin-American population provided by LARCG (Latin-American Renal Cancer Group) and analyze predictors of survival, recurrence and metastasis. A multi-institutional retrospective cohort study of 1523 patients submitted to surgical treatment for non-metastatic SRM from 1979 to 2016. Comparisons between radical (RN) or partial nephrectomy (PN) and young or elderly patients were performed. Kaplan-Meier curves and log-rank tests estimated 10-year overall survival. Predictors of local recurrence or metastasis were analyzed by a multivariable logistic regression model. PN and RN were performed in 897 (66%) and 461 (34%) patients. A proportional increase of PN cases from 48.5% (1979-2009) to 75% (after 2009) was evidenced. Stratifying by age, elderly patients (≥ 65 years) had better 10-year OS rates when submitted to PN (83.5%), than RN (54.5%), p = 0.044. This disparity was not evidenced in younger patients. On multivariable model, bilaterality, extracapsular extension and ASA (American Society of Anesthesiologists) classification ≥3 were predictors of local recurrence. We did not identify significant predictors for distant metastasis in our series. PN is performed in Latin-America in a similar proportion to developed areas and it has been increasing in the last years. Even in elderly individuals, if good functional status, sufficiently fit to surgery, and favorable tumor characteristics, they should be encouraged to perform PN. Intending to an earlier diagnosis of recurrence or distant metastasis, SRM cases with unfavorable characteristics should have a more rigorous follow-up routine. Kidney cancer Latin America Nephrectomy Nephron-sparing surgery Renal cell carcinoma Small renal masses in Latin-American population : Characteristics and prognostic factors for survival, recurrence and metastasis - A multi-institutional study from LARCG database