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               <dc:title>Cost-effectiveness of a programme to address sedentary behaviour in older adults : Results from the SITLESS RCT</dc:title>
               <dc:creator>Deidda, Manuela</dc:creator>
               <dc:creator>Coll-Planas, Laura</dc:creator>
               <dc:creator>Tully, Marl A.</dc:creator>
               <dc:creator>Giné-Garriga, Maria</dc:creator>
               <dc:creator>Kee, Frank</dc:creator>
               <dc:creator>Roqué i Figuls, Marta</dc:creator>
               <dc:creator>Blackburn, Nicole E.</dc:creator>
               <dc:creator>Guerra-Balic, Míriam</dc:creator>
               <dc:creator>Rothenbacher, Dietrich</dc:creator>
               <dc:creator>Dallmeier, Dhayana</dc:creator>
               <dc:creator>Caserotti, Paolo</dc:creator>
               <dc:creator>Skjødt, Mathias</dc:creator>
               <dc:creator>McIntosh, Emma</dc:creator>
               <dc:creator>Universitat Autònoma de Barcelona</dc:creator>
               <dc:subject>Aged</dc:subject>
               <dc:subject>Cost-Benefit Analysis</dc:subject>
               <dc:subject>Exercise</dc:subject>
               <dc:subject>Humans</dc:subject>
               <dc:subject>Quality-Adjusted Life Years</dc:subject>
               <dc:subject>Sedentary Behavior</dc:subject>
               <dc:subject>State Medicine</dc:subject>
               <dc:description>Background: This study details the within-trial economic evaluation and long-term economic model of SITLESS, a multi-country, three-armed randomized controlled trial comparing a combined intervention of exercise referral schemes (ERS) enhanced by self-management strategies (SMS) against ERS alone and usual care (UC). Methods: A cost-utility analysis, conducted from the base-case perspective of the National Health Service and personal and social services, estimated the incremental cost per incremental quality-adjusted life year (QALY) and years in full capability (YFC). A secondary analysis combined the costs with a broad set of outcomes within a cost-consequence framework, from a societal perspective. A Markov-type decision-analytic model was developed to project short-term changes in physical activity to long-term outcomes and costs, over a 5- and 15-year time horizon. Results: The results of the within-trial analysis show that SMS+ERS is highly likely to be cost-effective compared to ERS alone (ICER €4270/QALY), but not compared to UC. Participants allocated to the SMS+ERS group also showed an improvement in YFC compared to ERS alone and UC. The long-term analysis revealed that SMS+ERS is likely to be a cost-effective option compared to ERS and UC over a 5-year, but not with a 15-year horizon, being then dominated by ERS alone. Conclusion: This research provides new evidence that SMS is a cost-effective add-on to ERS strategies. This economic evaluation informs the case for further, cost-effective, refinement of lifestyle change programmes targeted to older adults, with the aim of ultimately reducing the impact of non-communicable diseases in this population.</dc:description>
               <dc:date>2022</dc:date>
               <dc:type>Article</dc:type>
               <dc:relation>European Commission 634270</dc:relation>
               <dc:relation>European journal of public health ; Vol. 32 Núm. 3 (january 2022), p. 415-421</dc:relation>
               <dc:rights>open access</dc:rights>
               <dc:rights>Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original.</dc:rights>
               <dc:rights>https://creativecommons.org/licenses/by/4.0/</dc:rights>
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