2026-04-13T01:42:55Zhttps://recercat.cat/oai/request

oai:recercat.cat:2072/4664222025-04-03T08:52:17Zcom_2072_98col_2072_378192

00925njm 22002777a 4500 dc Povsic, T.J. author Sanz-Ruiz, R. author Climent, A.M. author Bolli, R. author Taylor, D.A. author Gersh, B.J. author Menasché, P. author Perin, E.C. author Pompilio, G. author Atsma, D.E. author Badimon, Lina author DeMaria, A.N. author Hare, J.M. author Henry, Timothy D author Janssens, Stefan author Kastrup, J. author Torella, D. author Traverse, J.H. author Willerson, J.T. author Fernández Avilés, F. author 2021 The concept that cell-based repair of myocardial injury might be possible was introduced almost two decades ago; however, the field of cardiovascular reparative medicine has been criticized as translation to clinically effective approaches has been slow. The recent retraction of a series of papers has further impacted perception of this area of research. As researchers, clinicians, and teachers in this field, we felt it incumbent to critically appraise the current state of cardiac cell repair, determine what can be learned from past mistakes, and formulate best practices for future work. This special communication summarizes an introspective assessment of what has fallen short, how to prevent similar issues, and how the field might best move forward in the service of science and patients. Reparative cell therapy Myocardial repair and regeneration Stem cell therapy Reparative cell therapy for the heart : critical internal appraisal of the field in response to recent controversies