2026-04-17T03:53:56Zhttps://recercat.cat/oai/request

oai:recercat.cat:2072/4650972026-03-13T10:38:43Zcom_2072_98col_2072_378192

00925njm 22002777a 4500 dc Ortega, Emilio author Corcoy i Pla, Rosa author Gratacòs, Mònica author Cos Claramunt, Francesc Xavier author Mata-Cases, Manel author Puig Treserra, Ramon author Real, Jordi author Vlacho, Bogdan author Castelblanco, Esmeralda author Domingo Pedrol, Pedro author Khunti, Kamlesh author Franch-Nadal, Josep author Mauricio, Didac author Universitat Autònoma de Barcelona author 2021 Altres ajuts: Primary Care Diabetes Europe grant (grant number FEr20/0020). Aim This study's objective was to assess the risk of severe in-hospital complications of patients admitted for COVID-19 and diabetes mellitus (DM). Design This was a cross-sectional study. Settings We used pseudonymised medical record data provided by six general hospitals from the HM Hospitales group in Spain. Outcome measures Multiple logistic regression analyses were used to identify variables associated with mortality and the composite of mortality or invasive mechanical ventilation (IMV) in the overall population, and stratified for the presence or absence of DM. Spline analysis was conducted on the entire population to investigate the relationship between glucose levels at admission and outcomes. Results Overall, 1621 individuals without DM and 448 with DM were identified in the database. Patients with DM were on average 5.1 years older than those without. The overall in-hospital mortality was 18.6% (N=301), and was higher among patients with DM than those without (26.3% vs 11.3%; p<0.001). DM was independently associated with death, and death or IMV (OR=2.33, 95% CI: 1.7 to 3.1 and OR=2.11, 95% CI: 1.6 to 2.8, respectively; p<0.001). In subjects with DM, the only variables independently associated with both outcomes were age. Risk factors for severe outcomes in people with diabetes hospitalised for COVID-19 : A cross-sectional database study