2026-04-13T01:41:06Zhttps://recercat.cat/oai/request

oai:recercat.cat:2072/4629882025-04-03T08:10:54Zcom_2072_98col_2072_378192

00925njm 22002777a 4500 dc Parrón, Ignacio author Barrabeig, Irene author Alsedà, Miquel author Rius i Gibert, Maria Cristina author Cornejo-Sánchez, Thais author Jané i Checa, Mireia author Pérez, Cristina author Guix, Susana author Domínguez, Ángela author Working Group for the Study of Outbreaks of Acute Gastroenteritis in Catalonia author Universitat Autònoma de Barcelona author 2021 Norovirus is the leading cause of outbreaks of acute viral gastroenteritis. We carried out this study to investigate outbreaks in long-term care facilities reported in 2017 and 2018 in Catalonia (Spain). The characteristics of the centers, exposed persons and the genogroups responsible were analyzed. Viral loads were estimated. The attack rate (AR) of the outbreaks studied, and the rate ratio (RR) and the odds ratio (OR) and their 95% confidence intervals as measures of association were calculated. The mean cycle thresholds were compared using the t-test for independent means. We included 30 outbreaks (4631 exposed people). The global AR was 25.93%. The RR of residents vs. staff was 2.28 (95% CI 2.0-2.6). The RR between AR in residents with total or severe dependence vs. residents with moderate, low or no-dependence was 1.23 (95% CI 1.05-1.45). The AR were higher in smaller centers than in larger ones (38.47% vs. 19.25% and RR 2; 95% CI 1.82-2.2). GII was responsible for 70% of outbreaks. No association was found between the genogroup and presenting symptoms (OR 0.96; 95% CI 0.41-2.26). Viral loads were higher in symptomatic than in asymptomatic patients (p = 0.001). Adult Aged Aged, 80 and over Caliciviridae Infections Disease Outbreaks Female Gastroenteritis Humans Long-Term Care Male Middle Aged Norovirus Nursing Homes Prospective Studies Spain Young Adult Norovirus outbreaks in long-term care facilities in Catalonia from 2017 to 2018