2026-04-13T01:26:40Zhttps://recercat.cat/oai/request
oai:recercat.cat:2072/4587272026-03-13T07:57:23Zcom_2072_98col_2072_378192
RECERCAT author Frangou, Sophia author Modabbernia, Amirhossein author Williams, Steven C. R. author Papachristou, Efstathios author Doucet, Gaelle E. author Agartz, Ingrid author Aghajani, Moji author Akudjedu, Theophilus author Albajes-Eizagirre, Anton author Alnæs, Dag author Alpert, Kathryn I. author Andersson, Micael author Andreasen, Nancy C. author Andreassen, Ole A. author Asherson, Philip author Banaschewski, Tobias author Bargalló, Núria author Baumeister, Sarah author Baur-Streubel, Ramona author Bertolino, Alessandro author Bonvino, Aurora author Boomsma, Dorret I. author Borgwardt, Stefan author Bourque, Josiane author Brandeis, Daniel author Breier, Alan author Brodaty, Henry author Brouwer, Rachel M. author Buitelaar, Jan author Busatto, Geraldo F. author Buckner, Randy author Calhoun, Vince author Canales-Rodriguez, Erick Jorge author Cannon, Dara M. author Caseras, Xavier author Castellanos, Francisco X. author Cervenka, Simon author Chaim-Avancini, Tiffany M. author Ching, Christopher R. K. author Chubar, Victoria author Clark, Vincent P. author Conrod, Patricia author Conzelmann, Annette author Crespo-Facorro, Benedicto author Crivello, Fabrice author Crone, Eveline A. author Dale, Anders M. author Dannlowski, Udo author Davey, Christopher author de Geus, Eco J. C. author Haan, Lieuwe de, 1960- author de Zubicaray, Greig author den Braber, A. author Dickie, Erin W. author Di Giorgio, Annabella author Doan, Nhat Trung author Dørum, Erlend S. author Ehrlich, Stefan author Erk, Susanne author Espeseth, Thomas author Fatouros-Bergman, Helena author Fisher, Simon E. author Fouche, Jean-Paul author Franke, Barbara author Frodl, Thomas author Fuentes-Claramonte, Paola author Glahn, David C. author Gotlib, Ian H. author Grabe, Hans-Jörgen author Grimm, Oliver author Groenewold, Nynke A. author Grotegerd, Dominik author Gruber, Oliver author Gruner, Patricia author Gur, Raquel E. author Gur, Ruben C. author Hahn, Tim author Harrison, Ben J. author Hartman, Catharina A. author Hatton, Sean N. author Heinz, Andreas author Heslenfeld, Dirk J. author Hibar, Derrek P. author Hickie, Ian B. author Ho, Beng-Choon author Hoekstra, Pieter J. author Hohmann, Sarah author Holmes, Avram J. author Hoogman, Martine author Hosten, Norbert author Howells, Fleur M. author Hulshoff Pol, Hilleke E. author Huyser, Chaim author Jahanshad, Neda author James, Anthony author Jernigan, Terry L. author Jiang, Jiyang author Jönsson, Erik G. author Joska, John A. author Kahn, Rene author Kalnin, Andrew author Kanai, Ryota author Klein, Marieke author Klyushnik, Tatyana P. author Koenders, Laura author Koops, Sanne author Krämer, Bernd author Kuntsi, Jonna author Lagopoulos, Jim author Lázaro, Luisa author Lebedeva, Irina author Lee, Won Hee author Lesch, Klaus-Peter author Lochner, Christine author Machielsen, Marise W. J. author Maingault, Sophie author Martin, Nicholas G. author Martínez-Zalacaín, Ignacio author Mataix-Cols, David author Mazoyer, Bernard author McDonald, Colm author McDonald, Brenna C. author McIntosh, Andrew M. author McMahon, Katie L. author McPhilemy, Genevieve author Meinert, Susanne author Menchón Magriñá, José Manuel author Medland, Sarah Elizabeth author Meyer-Lindenberg, Andreas author Naaijen, Jilly author Najt, Pablo author Nakao, Tomohiro author Nordvik, Jan E. author Nyberg, Lars author Oosterlaan, Jaap author de la Foz, Víctor Ortiz-García author Paloyelis, Yannis author Pauli, Paul author Pergola, Giulio author Pomarol-Clotet, Edith author Portella Moll, Maria J., 1975- author Potkin, Steven G. author Radua, Joaquim author Reif, Andreas author Rinker, Daniel A. author Roffman, Joshua L. author Rosa, Pedro G. P. author Sacchet, Matthew D. author Sachdev, Perminder S. author Salvador, Raymond author Sánchez-Juan, Pascual author Sarró, Salvador author Satterthwaite, Theodore D. author Saykin, Andrew J. author Serpa, Mauricio H. author Schmaal, Lianne author Schnell, Knut author Schumann, Gunter author Sim, Kang author Smoller, Jordan W. author Sommer, Iris author Soriano-Mas, Carles author Stein, Dan J. author Strike, Lachlan author Swagerman, Suzanne C. author Tamnes, Christian K. author Temmingh, Henk S. author Thomopoulos, Sophia I. author Tomyshev, Alexander S. author Tordesillas-Gutiérrez, Diana author Trollor, Julian author Turner, Jessica A. author Uhlmann, Anne author van den Heuvel, Odile A. author van den Meer, Dennis author Van der Wee, Nic J. A. author van Haren, Neeltje E. M. author van 't Ent, Dennis author van Erp, Theo G. M. author Veer, Ilya M. author Veltman, Dick J. author Voineskos, Aristotle author Völzke, Henry author Walter, Henrik author Walton, Esther author Wang, Lei author Wang, Yang author Wassink, Thomas H. author Weber, Bernd author Wen, Wei author West, John D. author Westlye, Lars T. author Whalley, Heather author Wierenga, Lara M. author Wittfeld, Katharina author Wolf, Daniel H. author Worker, Amanda author Wright, Margaret J. author Yang, Kun author Yoncheva, Yuliya N. author Zanetti, Marcus Vinicius author Ziegler, Georg C. author Thompson, Paul M. author Dima, Danai author Universitat Autònoma de Barcelona 2021 Delineating the association of age and cortical thickness in healthy individuals is critical given the association of cortical thickness with cognition and behavior. Previous research has shown that robust estimates of the association between age and brain morphometry require large-scale studies. In response, we used cross-sectional data from 17,075 individuals aged 3-90 years from the Enhancing Neuroimaging Genetics through Meta-Analysis (ENIGMA) Consortium to infer age-related changes in cortical thickness. We used fractional polynomial (FP) regression to quantify the association between age and cortical thickness, and we computed normalized growth centiles using the parametric Lambda, Mu, and Sigma method. Interindividual variability was estimated using meta-analysis and one-way analysis of variance. For most regions, their highest cortical thickness value was observed in childhood. Age and cortical thickness showed a negative association; the slope was steeper up to the third decade of life and more gradual thereafter; notable exceptions to this general pattern were entorhinal, temporopolar, and anterior cingulate cortices. Interindividual variability was largest in temporal and frontal regions across the lifespan. Age and its FP combinations explained up to 59% variance in cortical thickness. These results may form the basis of further investigation on normative deviation in cortical thickness and its significance for behavioral and cognitive outcomes. We used cross-sectional data from 17,075 individuals aged 3-90 years from the Enhancing Neuroimaging Genetics through Meta-Analysis (ENIGMA) Consortium to infer age-related changes in cortical thickness. open access Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original. https://creativecommons.org/licenses/by/4.0/ Aging Cortical thickness Development Trajectories Cortical thickness across the lifespan : Data from 17,075 healthy individuals aged 3-90 years Article