2026-04-05T12:43:51Zhttps://recercat.cat/oai/request
oai:recercat.cat:2072/4553552024-10-31T05:37:38Zcom_2072_98col_2072_378192
RECERCAT author Rigo-Bonnin, Raúl author Díaz-Troyano, Noelia author García-Tejada, Laura author Marcè-Galindo, Albert author Valbuena-Asensio, Míriam author Canalias Reverter, Francesca 2024-10-31T05:37:38Z 2024-10-31T05:37:38Z 2020 http://hdl.handle.net/2072/455355 Clinicians request a large part of measurements of biological quantities that clinical laboratories perform for diagnostic, prognostic or diseases monitoring purposes. Thus, laboratories need to provide patient's results as reliable as possible. Metrological concepts like measurement uncertainty and metrological traceability allow to know the accuracy of these results and guarantee their comparability over time and space. Such is the importance of these two parameters that the estimation of measurement uncertainty and the knowledge of metrological traceability is required for clinical laboratories accredited by ISO 15189:2012. Despite there are many publications or guidelines to estimate the measurement uncertainty in clinical laboratories, it is not entirely clear what information and which formulae they should use to calculate it. On the other hand, unfortunately, there are a small number of clinical laboratories that know and describe the metrological traceability of their results, even though they are aware of the lack of comparability that currently exists for patient's results. Thus, to try to facilitate the task of clinical laboratories, this review aims to provide a proposal to estimate the measurement uncertainty. Also, different suggestions are shown to describe the metrological traceability. Measurement uncertainty estimation is partially based on the ISO/TS 20914:2019 guideline, and the metrological traceability described using the ISO 17511:2020. Different biological quantities routinely measured in clinical laboratories are used to exemplify the proposal and suggestions. open access Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original. https://creativecommons.org/licenses/by/4.0/ Biostatistics Quality control Standardization Traceability Uncertainty Estimation of the measurement uncertainty and practical suggestion for the description of the metrological traceability in clinical laboratories Article