2026-04-13T03:02:38Zhttps://recercat.cat/oai/request

oai:recercat.cat:2072/4300892026-03-13T04:56:44Zcom_2072_98col_2072_378192

00925njm 22002777a 4500 dc González, Carolina author Tabernero, David author Cortese, Maria Francesca author Gregori i Font, Josep author Casillas, Rosario author Riveiro Barciela, Mar author Godoy, Cristina author Sopena, Sara author Rando-Segura, Ariadna author Yll, Marçal author Lopez Martinez, Rosa author Quer, Josep author Esteban, Rafael author Buti, Maria author Rodríguez Frías, Francisco author 2018 To detect hyper-conserved regions in the hepatitis B virus (HBV) X gene (HBX) 5' region that could be candidates for gene therapy. The study included 27 chronic hepatitis B treatment-naive patients in various clinical stages (from chronic infection to cirrhosis and hepatocellular carcinoma, both HBeAg-negative and HBeAg-positive), and infected with HBV genotypes A-F and H. In a serum sample from each patient with viremia. Hepatitis B virus Hepatitis B X gene Hepatitis B X protein Gene therapy Next-generation sequencing HBV conserved regions Small interference RNA Detection of hyper-conserved regions in hepatitis B virus X gene potentially useful for gene therapy