2026-04-17T11:33:35Zhttps://recercat.cat/oai/request

oai:recercat.cat:2072/3748552024-12-20T17:07:38Zcom_2072_300912com_2072_4427col_2072_301309

Diastereodivergent Enantioselective [8+2] Annulation of Tro- pones and Enals Catalyzed by N-Heterocyclic Carbenes Wang, Shoulei Rodríguez-Escrich, Carles Fianchini, Mauro Maseras, Feliu Pericàs, Miquel A. 54 N-Heterocyclic carbene (NHC) catalysts are used for the first time to mediate asymmetric [8+2] cycloadditions of enals with tropones. The kinetic [8+2] cis-cycloadducts can be epimerized to their trans analogues by simply using increased amounts of base and longer reaction times. Substituted tropones are also tolerated, and the cycloaddition products can be derivatized by hydrogenation or methanolysis. The main stereochemical features on the results of DFT calculations. 2019-04-23 info:eu-repo/semantics/article info:eu-repo/semantics/acceptedVersion http://hdl.handle.net/2072/374855 https://doi.org/10.1021/acs.orglett.9b00906 eng CTQ2015-69136-R CTQ2017-87792-R DEC Generalitat de Ca- talunya (Grant 2014SGR827) L'accés als continguts d'aquest document queda condicionat a l'acceptació de les condicions d'ús establertes per la següent llicència Creative Commons:http://creativecommons.org/licenses/by-nc-nd/4.0/ info:eu-repo/semantics/openAccess 3187 p. application/pdf RECERCAT (Dipòsit de la Recerca de Catalunya)