2026-04-18T00:08:42Zhttps://recercat.cat/oai/request

oai:recercat.cat:2072/3685612024-12-20T23:18:05Zcom_2072_300912com_2072_4427col_2072_301309

Development of C2-Symmetric Chiral Bifunctional Triamines: Synthesis and Application in Asymmetric Organocatalysis Cañellas, Santiago Alonso, Pedro Pericas, Miquel A. 54 The synthesis and application of a newly designed C2-symmetric chiral bifunctional triamine family (C2-CBT) is reported. These enantiopure chiral triamine scaffolds can be accessed in multigram amounts from simple amino acids while avoiding chromatographic purification. As a proof of principle, C2-CBT has been studied in the aldol reaction of cyclic ketones with isatins, with the target tertiary alcohols being formed in a highly efficient manner. Catalyst recovery by simple extraction techniques and subsequent reuse has been performed. 2018-08-01 info:eu-repo/semantics/article info:eu-repo/semantics/acceptedVersion http://hdl.handle.net/2072/368561 https://doi.org/10.1021/acs.orglett.8b01957 eng Grant No. CTQ2015- 69136-R (AEI/MINECO/FEDER, UE) Grant No. 2014SGR827 SEV- 2013-0319 BES- 2015-072152 L'accés als continguts d'aquest document queda condicionat a l'acceptació de les condicions d'ús establertes per la següent llicència Creative Commons:http://creativecommons.org/licenses/by-nc-nd/4.0/ info:eu-repo/semantics/openAccess 4806 p. application/pdf RECERCAT (Dipòsit de la Recerca de Catalunya)