2026-04-13T07:18:37Zhttps://recercat.cat/oai/request

oai:recercat.cat:2072/3059242026-01-15T14:12:33Zcom_2072_300912com_2072_4427col_2072_301309

RECERCAT author Wu, Yichen author Izquierdo, Susana author Vidossich, Pietro author Lledos, Agustí author Shafir, Alexandr 2018-01-15T16:03:58Z2018-02-15T10:28:57Z2024-04-23T10:35:30Z 2018-01-15T16:03:58Z2018-02-15T10:28:57Z2024-04-23T10:35:30Z 2016 http://hdl.handle.net/2072/305924 https://doi.org/10.1002/anie.201602569 The synthesis of N-arylimidazoles substituted at the sterically encumbered 5-position is a challenge for modern synthetic approaches. A new family of imidazolyl aryliodonium salts is reported, which serve as a stepping stone on the way to selective formation of N1-aryl-5-iodoimidazoles. Iodine acts as a “universal” placeholder poised for replacement by aryl substituents. These new λ3-iodanes are produced by treating the NH-imidazole with ArI(OAc)2, and are converted to N1-aryl-5-iodoimidazoles by a selective copper-catalyzed aryl migration. The method tolerates a variety of aryl fragments and is also applicable to substituted imidazoles. eng NH-Heterocyclic Aryliodonium Salts and their Selective Conversion into N1-Aryl-5-iodoimidazoles info:eu-repo/semantics/article URL https://recercat.cat/bitstream/2072/305924/2/Shafir_ACIE2016.pdf File MD5 8618db02fbd05ac45ea982fa6dcaf92a 963250 application/pdf Shafir_ACIE2016.pdf URL https://recercat.cat/bitstream/2072/305924/1/Shafir_ACIE2016.pdf.txt File MD5 b20e10f9f09446255fc389a815d56c9f 20038 text/plain Shafir_ACIE2016.pdf.txt