2026-04-17T18:44:54Zhttps://recercat.cat/oai/request

oai:recercat.cat:2072/2295972024-12-13T09:23:40Zcom_2072_228903com_2072_96873com_2072_96852com_2072_2015col_2072_228904

Contamination of genomic databases by HIV-1 and its possible consequences. A study in Bioinformatics. Romero Fernández-Bravo, Miguel Ángel HIV-1 BLASTN Genomic Contamination VIH-1 bioinformatics bioinformàtica bioinformática Peer-reviewed The bioinformatics Basic Local Alignment Search Tools (BLASTN and TBLASTN) were used to search public databases for nucleic acid (NA) and amino acid (AA) sequences identical or similar to HIV-1 DNA and proteins. Several significant alignments were detected in a variety of non-HIV-1 taxa and other sources deposited in public genomic and protein repositories. Homologies between a number of HIV-1 proteins and those of Candida, Cryptococcus and Schistosoma mansoni are of uncertain significance and suggest the need for further analyses. The overwhelmingly likely cause for these data is contamination. info:eu-repo/semantics/article http://hdl.handle.net/10609/31361 eng <a href="http://creativecommons.org/licenses/by-nc-sa/3.0/es/">http://creativecommons.org/licenses/by-nc-sa/3.0/es/</a>