2026-04-17T12:50:10Zhttps://recercat.cat/oai/requestoai:recercat.cat:20.500.14342/54932025-09-13T23:58:18Zcom_2072_482405com_2072_183628col_2072_482414
RECERCAT
author
Santos, Nicolas
author
Fernandez Alarcon, Jennifer
author
Ahumada, Manuel
2025-07-07
2639-4979
http://hdl.handle.net/20.500.14342/5493
https://doi.org/10.1021/acsmaterialslett.5c00616
This review provides an overview of the current knowledge regarding the nanotoxicological impact of metal-based nanomaterials intended for biomedical applications. The extensive application of nanotechnology in the biomedical field has driven a surge in the development of nanomaterials, particularly those derived from metal sources. However, the numerous formulations, experimental conditions, and physicochemical and biological parameters have raised legitimate concerns about the safety and toxicity of these nanomaterials. To complicate matters, the interaction of nanoparticles with biological environments alters their physicochemical properties, including size, surface charge, and colloidal stability, where the exposure pathway is significant. Consequently, the nanotoxicological profile of the nanomaterial also changes. This review concisely presents the primary nanotoxicology mechanisms and findings in the literature. Additionally, it offers an overview of the current state of nanotoxicology for metal-based nanomaterials and provides brief recommendations for its evaluation.
eng
© American Chemical Society. Tots els drets reservats.
Cells
Metal Nanoparticles
Nanomaterials
Oxides
Toxicity
Cèl·lules
Nanopartícules
Òxids
Toxicologia
Understanding the Toxicity of Metal-Based Nanomaterials: Current Insights, Challenges, and Future Directions
info:eu-repo/semantics/article