2026-04-13T04:14:47Zhttps://recercat.cat/oai/request

oai:recercat.cat:20.500.14342/51622025-05-15T19:19:19Zcom_2072_482405com_2072_183628col_2072_482409

00925njm 22002777a 4500 dc Lista-Paz, Ana author Langer, Daniel author Barral-Fernández, Margarita author Quintela-del-Río, Alejandro author Gimeno-Santos, Elena author Arbillaga-Etxarri, Ane author Torres Castro, Rodrigo author Vilaro, Jordi author Varas de la Fuente, Ana B. author Serrano Veguillas, Cristina author Bravo Cortés, María Pilar author Martín Cortijo, Concepción author García Delgado, Esther author Herrero-Cortina, Beatriz author Valera, José Luis author Fregonezi, Guilherme Augusto de Freitas author González Montañez, Carolina author Martín-Valero, Rocío author Francín-Gallego, Marina author Sanesteban Hermida, Yolanda author Giménez Moolhuyzen, Esther author Álvarez Rivas, Jorge author Ríos-Cortés, Antonio T. author Souto Camba, Sonia author González Doniz, Luz author 2023-12 Introduction Maximal inspiratory and expiratory pressures (PImax/PEmax) reference equations obtained in healthy people are needed to correctly interpret respiratory muscle strength. Currently, no clear cut-off points defining respiratory muscle weakness are available. We aimed to establish sex-specific reference equations for PImax/PEmax in a large sample of healthy adults and to objectively determine cut-off points for respiratory muscle weakness. Methods A multicentre cross-sectional study was conducted across 14 Spanish centres. Healthy non-smoking volunteers aged 18–80 years stratified by sex and age were recruited. PImax/PEmax were assessed using uniform methodology according to international standards. Multiple linear regressions were used to obtain reference equations. Cut-off points for respiratory muscle weakness were established by using T-scores. Results The final sample consisted of 610 subjects (314 females; 48 [standard deviation, SD: 17] years). Reference equations for PImax/PEmax included body mass index and a squared term of the age as independent variables for both sexes (p < 0.01). Cut-off points for respiratory muscle weakness based on T-scores ≥2.5 SD below the peak mean value achieved at a young age were: 62 and 83 cmH2O for PImax and 81 and 109 cmH2O for PEmax in females and males, respectively. Conclusion These reference values, based on the largest dataset collected in a European population to date using uniform methodology, help identify cut-off points for respiratory muscle weakness in females and males. These data will help to better identify the presence of respiratory muscle weakness and to determine indications for interventions to improve respiratory muscle function. http://hdl.handle.net/20.500.14342/5162 https://doi.org/10.1016/j.arbres.2023.08.016 Pressions respiratòries màximes Músculs respiratoris Aparell respiratori -- Proves funcionals Força muscular Valors de referència (Medicina) Voluntaris Adults Maximal respiratory pressure reference equations in healthy adults and cut-off points for defining respiratory muscle weakness