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oai:recercat.cat:20.500.14342/51332025-05-15T19:19:16Zcom_2072_482405com_2072_183628col_2072_482409

00925njm 22002777a 4500 dc Marhuenda-Muñoz, María author Rinaldi de Alvarenga, José Fernando author Hernáez, Álvaro author Tresserra-Rimbau, Anna author Martínez-González, Miguel Ángel author Salas Salvadó, Jordi author Corella Piquer, Dolores author Malcampo, Mireia author Alfredo Martínez, J. author Alonso Gómez, Ángel M. author Wärnberg, Julia author Vioque, Jesús author Romaguera, Dora author López Miranda, José author Estruch Riba, Ramon author Tinahones Madueño, Francisco J. author Lapetra, José author Serra Majem, Lluís author Bueno-Cavanillas, Aurora author Tur, Josep A. author Martín Sánchez, Vicente author Pintó Sala, Xavier author Delgado-Rodríguez, Miguel author Matía Martín, Pilar author Vidal, Josep author Vázquez, Clotilde author Daimiel, Lidia author Ros Rahola, Emilio author Serra-Mir, Mercè author Vázquez Ruiz, Zenaida author Nishi, Stephanie K. author Sorlí, José V. author Zomeño, M. Dolores author Zulet, M. Angeles author Vaquero Luna, Jessica author Carabaño-Moral, Rosa author Notario Barandiaran, Leyre author Morey, M. author Garcia-Rios, Antonio author Gómez-Pérez, Ana Maria author Santos Lozano, José Manuel author Buil Cosiales, Pilar author Basora, Josep author Portolés, Olga author Schröder, Helmut author Abete, Itziar author Salaverria, Itziar author Toledo, Estefanía author Babio, Nancy author Fitó Colomer, Montserrat author Martínez-Huélamo, Miriam author Lamuela Raventós, Rosa Ma. author 2021-03 Carotenoids are pigments contained mainly in fruit and vegetables (F&V) that have beneficial effects on cardiometabolic health. Due to their lipophilic nature, co-ingestion of fat appears to increase their bioavailability via facilitating transfer to the aqueous micellar phase during digestion. However, the extent to which high fat intake may contribute to increased carotenoid plasma concentrations is still unclear. The objective was to examine the degree to which the consumption of different amounts of both carotenoid-rich foods and fats is associated with plasma carotenoid concentrations within a Mediterranean lifestyle context (subsample from the PREDIMED-Plus study baseline) where consumption of F&V and fat is high. The study population was categorized into four groups according to their self-reported consumption of F&V and fat. Carotenoids were extracted from plasma samples and analyzed by HPLC-UV-VIS-QqQ-MS/MS. Carotenoid systemic concentrations were greater in high consumers of F&V than in low consumers of these foods (+3.04 μmol/L (95% CI: 0.90, 5.17), p-value = 0.005), but circulating concentrations seemed to decrease when total fat intake was very high (−2.69 μmol/L (−5.54; 0.16), p-value = 0.064). High consumption of F&V is associated with greater systemic levels of total carotenoids, in particular when fat intake is low-to-moderate rather than very high. http://hdl.handle.net/20.500.14342/5133 https://doi.org/10.3390/ antiox10030473 Compostos bioactius Fitoquímics Olis i greixos comestibles Dieta mediterrània PREDIMED-Plus Carotenoides plasmàtics Absorció (Fisiologia) Cromatografia de líquids Espectometria de masses High fruit and vegetable consumption and moderate fat intake are associated with higher carotenoid concentration in human plasma