2026-04-14T07:22:06Zhttps://recercat.cat/oai/request

oai:recercat.cat:20.500.12328/51562025-12-16T06:08:28Zcom_2072_67741col_2072_484352

Mask wearing by COVID-19 index cases reduces SARS-CoV-2 transmission to household contacts Godoy, Pere Pardos, Jessica García Cenoz, Manuel Parron, Ignacio Martínez-Baz, Iván Ferras, Joaquim Rius, Cristina Godoy, Sofia Toledo, Diana Sanz, Inmaculada Follia, Nuria Miret Lopez, Carme Alsedà, Miquel Plans-Rubió, Pedro Carol, Monica Bes, Nuria Sala, Maria Rosa Caylà, Joan A. Muñoz-Almagro, Carmen Castilla, Jesús Domínguez, Ángela SARS-CoV-2 Transmission to Household Contacts Working Group (PI21/01883 and ESP22PI01) COVID-19 Facemask Household contact SARS-CoV-2 Mascarilla Contacto domiciliario Mascareta Contacte domiciliari The objective of this study was to evaluate the impact on SARS-CoV-2 transmission prevention of mask wearing by index cases and their household contacts. A prospective study of SARS-CoV-2 transmission to household contacts aged ≥18 years was conducted between May 2022 and February 2024 in Spain. Contacts underwent a rapid antigen test on day zero and a real-time polymerase chain reaction test 7 days later if results were negative. The dependent variable was SARS-CoV-2 infection in contacts. Index case and contact mask use effects were estimated using the adjusted odds ratio (aOR) and its 95% confidence interval (CI). Studied were 230 household contacts, mean (standard deviation) age 53.3 (16.6) years, and 47.8% (110/230) women. Following index case diagnosis, 36.1% of contacts (83/230) used a mask, and 54.3% (125/230) were exposed to a mask-wearing index case. Infection incidence in contacts was 45.2% (104/230) and was lower in contacts exposed to mask-wearing index cases (36.0% vs. 56.2%; p < 0.002). The logistic regression model indicated a protective effect for contacts of both index case mask use (aOR = 0.31; 95% CI: 0.15–0.65) and vaccination (aOR = 0.24; 95% CI: 0.08–0.77). Index case mask use reduced SARS-CoV-2 transmission to contacts, while mask effectiveness was not observed for contacts. 2025-12-16T06:08:27Z 2025-12-16T06:08:27Z 2025-12-16T06:08:27Z 2025-10-06 info:eu-repo/semantics/article Godoy, Pere; Pardos, Jessica; García Cenoz, Manuel[et al.]. Mask wearing by COVID-19 index cases reduces SARS-CoV-2 transmission to household contacts. Epidemiology and Infection, 2025, 153, e125. Disponible en <https://pmc.ncbi.nlm.nih.gov/articles/PMC12571686/>. Fecha de acceso: 15 dic. 2025. DOI: 10.1017/S0950268825100642 0950-2688 http://hdl.handle.net/20.500.12328/5156 https://dx.doi.org/10.1017/S0950268825100642 eng Epidemiology and Infection 153 http:// creativecommons.org/licenses/by/4.0 info:eu-repo/semantics/openAccess © The Author(s), 2025. Published by Cambridge University Press. This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http:// creativecommons.org/licenses/by/4.0), which permits unrestricted re-use, distribution and reproduction, provided the original article is properly cited. Cambridge University Press