2026-04-14T04:29:26Zhttps://recercat.cat/oai/requestoai:recercat.cat:20.500.12328/51562025-12-16T06:08:28Zcom_2072_67741col_2072_484352
RECERCAT
author
Godoy, Pere
author
Pardos, Jessica
author
García Cenoz, Manuel
author
Parron, Ignacio
author
Martínez-Baz, Iván
author
Ferras, Joaquim
author
Rius, Cristina
author
Godoy, Sofia
author
Toledo, Diana
author
Sanz, Inmaculada
author
Follia, Nuria
author
Miret Lopez, Carme
author
Alsedà, Miquel
author
Plans-Rubió, Pedro
author
Carol, Monica
author
Bes, Nuria
author
Sala, Maria Rosa
author
Caylà, Joan A.
author
Muñoz-Almagro, Carmen
author
Castilla, Jesús
author
Domínguez, Ángela
author
SARS-CoV-2 Transmission to Household Contacts Working Group (PI21/01883 and ESP22PI01)
2025-12-16T06:08:27Z
2025-12-16T06:08:27Z
2025-10-06
Godoy, Pere; Pardos, Jessica; García Cenoz, Manuel[et al.]. Mask wearing by COVID-19 index cases reduces SARS-CoV-2 transmission to household contacts. Epidemiology and Infection, 2025, 153, e125. Disponible en <https://pmc.ncbi.nlm.nih.gov/articles/PMC12571686/>. Fecha de acceso: 15 dic. 2025. DOI: 10.1017/S0950268825100642
0950-2688
http://hdl.handle.net/20.500.12328/5156
https://dx.doi.org/10.1017/S0950268825100642
The objective of this study was to evaluate the impact on SARS-CoV-2 transmission prevention
of mask wearing by index cases and their household contacts. A prospective study of SARS-CoV-2
transmission to household contacts aged ≥18 years was conducted between May 2022 and
February 2024 in Spain. Contacts underwent a rapid antigen test on day zero and a real-time
polymerase chain reaction test 7 days later if results were negative. The dependent variable was
SARS-CoV-2 infection in contacts. Index case and contact mask use effects were estimated
using the adjusted odds ratio (aOR) and its 95% confidence interval (CI). Studied were
230 household contacts, mean (standard deviation) age 53.3 (16.6) years, and 47.8%
(110/230) women. Following index case diagnosis, 36.1% of contacts (83/230) used a mask,
and 54.3% (125/230) were exposed to a mask-wearing index case. Infection incidence in
contacts was 45.2% (104/230) and was lower in contacts exposed to mask-wearing index cases
(36.0% vs. 56.2%; p < 0.002). The logistic regression model indicated a protective effect for
contacts of both index case mask use (aOR = 0.31; 95% CI: 0.15–0.65) and vaccination
(aOR = 0.24; 95% CI: 0.08–0.77). Index case mask use reduced SARS-CoV-2 transmission
to contacts, while mask effectiveness was not observed for contacts.
eng
© The Author(s), 2025. Published by Cambridge
University Press. This is an Open Access article,
distributed under the terms of the Creative
Commons Attribution licence (http://
creativecommons.org/licenses/by/4.0), which
permits unrestricted re-use, distribution and
reproduction, provided the original article is
properly cited.
COVID-19
Facemask
Household contact
SARS-CoV-2
Mascarilla
Contacto domiciliario
Mascareta
Contacte domiciliari
Mask wearing by COVID-19 index cases reduces SARS-CoV-2 transmission to household contacts
info:eu-repo/semantics/article