<?xml version="1.0" encoding="UTF-8"?><?xml-stylesheet type="text/xsl" href="static/style.xsl"?><OAI-PMH xmlns="http://www.openarchives.org/OAI/2.0/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/ http://www.openarchives.org/OAI/2.0/OAI-PMH.xsd"><responseDate>2026-04-18T07:44:09Z</responseDate><request verb="GetRecord" identifier="oai:www.recercat.cat:20.500.12328/5147" metadataPrefix="mets">https://recercat.cat/oai/request</request><GetRecord><record><header><identifier>oai:recercat.cat:20.500.12328/5147</identifier><datestamp>2025-12-05T14:50:11Z</datestamp><setSpec>com_2072_67741</setSpec><setSpec>col_2072_484352</setSpec></header><metadata><mets xmlns="http://www.loc.gov/METS/" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:doc="http://www.lyncode.com/xoai" ID="&#xa;&#x9;&#x9;&#x9;&#x9;DSpace_ITEM_20.500.12328-5147" TYPE="DSpace ITEM" PROFILE="DSpace METS SIP Profile 1.0" xsi:schemaLocation="http://www.loc.gov/METS/ http://www.loc.gov/standards/mets/mets.xsd" OBJID="&#xa;&#x9;&#x9;&#x9;&#x9;hdl:20.500.12328/5147">
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                  <mods:namePart>Gutiérrez Ruiz, Xavier</mods:namePart>
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                  <mods:namePart>Cano-Batalla, Jordi</mods:namePart>
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                  <mods:namePart>Figueras, Oscar</mods:namePart>
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                  <mods:namePart>Real-Voltas, Francisco</mods:namePart>
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               <mods:name>
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                     <mods:roleTerm type="text">author</mods:roleTerm>
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                  <mods:namePart>NÚÑEZ BIELSA, ELENA</mods:namePart>
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               <mods:name>
                  <mods:role>
                     <mods:roleTerm type="text">author</mods:roleTerm>
                  </mods:role>
                  <mods:namePart>Cabratosa-Termes, Josep</mods:namePart>
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                  <mods:dateAccessioned encoding="iso8601">2025-12-05T14:50:11Z</mods:dateAccessioned>
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                  <mods:dateIssued encoding="iso8601">2025-11-26</mods:dateIssued>
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               <mods:identifier type="citation">Gutiérrez-Ruiz, Xavier; Cano-Batalla, Jordi; Figueras-Álvarez, Óscar[et al.]. In Vitro Effect of Sequential Compressive Loading and Thermocycling on Marginal Microleakage of Digitally Fabricated Overlay Restorations Made from Five Materials. Applied sciences, 2025, 15(23), 12532. Disponible en &lt;https://www.mdpi.com/3606740>. Fecha de acceso: 27 nov. 2025. DOI: 10.3390/app152312532</mods:identifier>
               <mods:identifier type="issn">2076-3417</mods:identifier>
               <mods:identifier type="uri">http://hdl.handle.net/20.500.12328/5147</mods:identifier>
               <mods:identifier type="doi">10.3390/app152312532</mods:identifier>
               <mods:abstract>Marginal microleakage compromises the longevity and biological seal of indirect restorations. Despite the growing adoption of computer-aided design and manufacturing&#xd;
(CAD/CAM) and three-dimensional (3D) printing technologies, limited evidence compares the marginal integrity of these materials under combined mechanical and thermal&#xd;
stresses. This study evaluated and compared the marginal microleakage of overlay restorations fabricated from five contemporary restorative materials, IPS e.max® ZirCAD Prime,&#xd;
BioHPP®, G-CAM, VarseoSmile CrownPlus, and IPS e.max® CAD, after sequential compressive loading and thermocycling. A total of 125 extracted human molars were prepared for&#xd;
standardized 1.5 mm-thick CAD/CAM overlay restorations and assigned to three experimental conditions: control, sequential compressive loading (3 × 500 N), and thermocycling&#xd;
(6000 cycles between 5 ◦C and 55 ◦C) followed by loading. Microleakage was assessed&#xd;
using 2% methylene blue dye and stereomicroscopy. Data were analyzed using Fisher’s&#xd;
exact test and Fleiss’ Kappa (α = 0.05). G-CAM and IPS e.max® ZirCAD Prime exhibited&#xd;
the lowest microleakage across all testing conditions, while BioHPP® showed the highest&#xd;
values. Both sequential compressive loadings and thermocycling significantly increased&#xd;
microleakage in all materials (p &lt; 0.001). The results indicate that material type significantly&#xd;
influences marginal sealing, with G-CAM and IPS e.max® ZirCAD Prime maintaining&#xd;
superior marginal integrity compared with other materials tested.</mods:abstract>
               <mods:language>
                  <mods:languageTerm authority="rfc3066">spa</mods:languageTerm>
               </mods:language>
               <mods:accessCondition type="useAndReproduction">© 2025 by the authors.&#xd;
Licensee MDPI, Basel, Switzerland.&#xd;
This article is an open access article&#xd;
distributed under the terms and&#xd;
conditions of the Creative Commons&#xd;
Attribution (CC BY) license&#xd;
(https://creativecommons.org/&#xd;
licenses/by/4.0/)</mods:accessCondition>
               <mods:subject>
                  <mods:topic>CAD/CAM</mods:topic>
               </mods:subject>
               <mods:subject>
                  <mods:topic>Microleakage</mods:topic>
               </mods:subject>
               <mods:subject>
                  <mods:topic>Overlay restorations</mods:topic>
               </mods:subject>
               <mods:subject>
                  <mods:topic>Thermocycling</mods:topic>
               </mods:subject>
               <mods:subject>
                  <mods:topic>Sequential compressive loadings</mods:topic>
               </mods:subject>
               <mods:subject>
                  <mods:topic>Zirconia</mods:topic>
               </mods:subject>
               <mods:subject>
                  <mods:topic>High-performance polymers</mods:topic>
               </mods:subject>
               <mods:subject>
                  <mods:topic>Microfiltración</mods:topic>
               </mods:subject>
               <mods:subject>
                  <mods:topic>Restauraciones superpuestas</mods:topic>
               </mods:subject>
               <mods:subject>
                  <mods:topic>Termoterapia</mods:topic>
               </mods:subject>
               <mods:subject>
                  <mods:topic>Circonita</mods:topic>
               </mods:subject>
               <mods:subject>
                  <mods:topic>Polímeros de alto rendimiento</mods:topic>
               </mods:subject>
               <mods:subject>
                  <mods:topic>Cargas compresivas secuenciales</mods:topic>
               </mods:subject>
               <mods:subject>
                  <mods:topic>Microfiltració</mods:topic>
               </mods:subject>
               <mods:subject>
                  <mods:topic>Restauracions superposades</mods:topic>
               </mods:subject>
               <mods:subject>
                  <mods:topic>Termoteràpia</mods:topic>
               </mods:subject>
               <mods:subject>
                  <mods:topic>Zircònia</mods:topic>
               </mods:subject>
               <mods:subject>
                  <mods:topic>Polímers d'alt rendiment</mods:topic>
               </mods:subject>
               <mods:subject>
                  <mods:topic>Càrregues compressives seqüencials</mods:topic>
               </mods:subject>
               <mods:titleInfo>
                  <mods:title>In Vitro Effect of Sequential Compressive Loading and Thermocycling on Marginal Microleakage of Digitally Fabricated Overlay Restorations Made from Five Materials</mods:title>
               </mods:titleInfo>
               <mods:genre>info:eu-repo/semantics/article</mods:genre>
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