2026-04-17T10:20:57Zhttps://recercat.cat/oai/requestoai:recercat.cat:20.500.12328/35362025-05-16T12:47:15Zcom_2072_67741col_2072_484352
RECERCAT
author
Monje, Alberto
author
Pons, Ramón
author
Vilarrasa, Javi
author
Nart, José
author
Wang, Hom-Lay
2025-05-16T12:47:15Z
2025-05-16T12:47:15Z
2022
Monje, Alberto; Pons, Ramón; Vilarrasa, Javi [et al.]. Significance of barrier membrane on the reconstructive therapy of peri-implantitis: a randomized controlled trial. Journal of Periodontology, 2022, p. 1-13. Disponible en: <https://aap.onlinelibrary.wiley.com/doi/10.1002/JPER.22-0511>. Fecha de acceso: 17 ene. 2023. DOI: 10.1002/JPER.22-0511
1943-3670
http://hdl.handle.net/20.500.12328/3536
https://dx.doi.org/10.1002/JPER.22-0511
Background: he objective of this trial was to investigate the clinical and radiographic significance of using a mixture of mineralized and demineralized allografts in combination (M) or not (NM) with a resorbable cross-linked barrier membrane in the reconstructive therapy of peri-implantitis defects. Methods: A two-arm randomized clinical trial was performed in patients diagnosed with peri-implantitis that exhibited contained defects. Clinical parameters were recorded at baseline (T0), 6 months (T1), and 12 months (T2). Radiographic parameters were recorded at T0 and T2. A composite criterion for disease resolution was defined a priori. A generalized linear model of repeated measures with generalized estimation equation statistical methods was used. Results: Overall, 33 patients (nimplants = 48) completed the study. At T2, mean disease resolution was 77.1%. The use of a barrier membrane did not enhance the probability of disease resolution at T2 (odds ratio [OR] = 1.55, p = 0.737). Conversely, the odds of disease resolution were statistically associated with the modified plaque index recorded at T0 (OR = 0.13, p = 0.006) and keratinized mucosa width (OR = 2.10, p = 0.035). Moreover, women exhibited greater odds to show disease resolution (OR = 5.56, p = 0.02). Conclusion: Reconstructive therapy by means of a mixture of mineralized and demineralized allografts is effective in clinically resolving peri-implantitis and in gaining radiographic marginal bone level. The addition of a barrier membrane to reconstructive therapy of peri-implantitis does not seem to enhance the outcomes of contained bone defects (NCT05282667).
eng
© 2022 The Authors.Journal of Periodontologypublished by Wiley Periodicals LLC on behalf of American Academy of Periodontology.
Materials biocompatibles
Implants dentals
Mandíbula
Periimplantitis
Regeneració
Cicatrització de ferides
Materiales biocompatibles
Implantes dentales
Mandíbula
Periimplantitis
Regeneración
Cicatrización de heridas
Biocompatible materials
Dental implants
Jaw
Peri-implantitis
Regeneration
Wound healing
Significance of barrier membrane on the reconstructive therapy of peri-implantitis: a randomized controlled trial
info:eu-repo/semantics/article