2026-04-17T11:27:33Zhttps://recercat.cat/oai/request

oai:recercat.cat:20.500.12328/35362025-05-16T12:47:15Zcom_2072_67741col_2072_484352

00925njm 22002777a 4500 dc Monje, Alberto author Pons, Ramón author Vilarrasa, Javi author Nart, José author Wang, Hom-Lay author 2022 Background: he objective of this trial was to investigate the clinical and radiographic significance of using a mixture of mineralized and demineralized allografts in combination (M) or not (NM) with a resorbable cross-linked barrier membrane in the reconstructive therapy of peri-implantitis defects. Methods: A two-arm randomized clinical trial was performed in patients diagnosed with peri-implantitis that exhibited contained defects. Clinical parameters were recorded at baseline (T0), 6 months (T1), and 12 months (T2). Radiographic parameters were recorded at T0 and T2. A composite criterion for disease resolution was defined a priori. A generalized linear model of repeated measures with generalized estimation equation statistical methods was used. Results: Overall, 33 patients (nimplants = 48) completed the study. At T2, mean disease resolution was 77.1%. The use of a barrier membrane did not enhance the probability of disease resolution at T2 (odds ratio [OR] = 1.55, p = 0.737). Conversely, the odds of disease resolution were statistically associated with the modified plaque index recorded at T0 (OR = 0.13, p = 0.006) and keratinized mucosa width (OR = 2.10, p = 0.035). Moreover, women exhibited greater odds to show disease resolution (OR = 5.56, p = 0.02). Conclusion: Reconstructive therapy by means of a mixture of mineralized and demineralized allografts is effective in clinically resolving peri-implantitis and in gaining radiographic marginal bone level. The addition of a barrier membrane to reconstructive therapy of peri-implantitis does not seem to enhance the outcomes of contained bone defects (NCT05282667). Monje, Alberto; Pons, Ramón; Vilarrasa, Javi [et al.]. Significance of barrier membrane on the reconstructive therapy of peri-implantitis: a randomized controlled trial. Journal of Periodontology, 2022, p. 1-13. Disponible en: <https://aap.onlinelibrary.wiley.com/doi/10.1002/JPER.22-0511>. Fecha de acceso: 17 ene. 2023. DOI: 10.1002/JPER.22-0511 1943-3670 http://hdl.handle.net/20.500.12328/3536 https://dx.doi.org/10.1002/JPER.22-0511 Materials biocompatibles Implants dentals Mandíbula Periimplantitis Regeneració Cicatrització de ferides Materiales biocompatibles Implantes dentales Mandíbula Periimplantitis Regeneración Cicatrización de heridas Biocompatible materials Dental implants Jaw Peri-implantitis Regeneration Wound healing Significance of barrier membrane on the reconstructive therapy of peri-implantitis: a randomized controlled trial