2026-04-14T02:10:17Zhttps://recercat.cat/oai/requestoai:recercat.cat:20.500.12328/34632025-05-16T12:55:28Zcom_2072_67741col_2072_484352
RECERCAT
author
RUBIO-PALAU, JOSEP
author
COVIDSurg Collaborative
author
GlobalSurg Collaborative
2025-05-16T12:55:28Z
2025-05-16T12:55:28Z
2021
COVIDSurg Collaborative; GlobalSurg Collaborative. Timing of surgery following SARS-CoV-2 infection: an international prospective cohort study. Anaesthesia, 2021, 76, p. 748-758. Disponible en: <https://associationofanaesthetists-publications.onlinelibrary.wiley.com/doi/10.1111/anae.15458>. Fecha de acceso: 21 oct. 2022. DOI: 10.1111/anae.15458
1365-2044
http://hdl.handle.net/20.500.12328/3463
https://dx.doi.org/10.1111/anae.15458
Peri-operative SARS-CoV-2 infection increases postoperative mortality. The aim of this study was to determine the optimal duration of planned delay before surgery in patients who have had SARS-CoV-2 infection. This international, multicentre, prospective cohort study included patients undergoing elective or emergency surgery during October 2020. Surgical patients with pre-operative SARS-CoV-2 infection were compared with those without previous SARS-CoV-2 infection. The primary outcome measure was 30-day postoperative mortality. Logistic regression models were used to calculate adjusted 30-day mortality rates stratified by time from diagnosis of SARS-CoV-2 infection to surgery. Among 140,231 patients (116 countries), 3127 patients (2.2%) had a pre-operative SARS-CoV-2 diagnosis. Adjusted 30-day mortality in patients without SARS-CoV-2 infection was 1.5% (95%CI 1.4–1.5). In patients with a pre-operative SARS-CoV-2 diagnosis, mortality was increased in patients having surgery within 0–2 weeks, 3–4 weeks and 5–6 weeks of the diagnosis (odds ratio (95%CI) 4.1 (3.3–4.8), 3.9 (2.6–5.1) and 3.6 (2.0–5.2), respectively). Surgery performed ≥ 7 weeks after SARS-CoV-2 diagnosis was associated with a similar mortality risk to baseline (odds ratio (95%CI) 1.5 (0.9–2.1)). After a ≥ 7 week delay in undertaking surgery following SARS-CoV-2 infection, patients with ongoing symptoms had a higher mortality than patients whose symptoms had resolved or who had been asymptomatic (6.0% (95%CI 3.2–8.7) vs. 2.4% (95%CI 1.4–3.4) vs. 1.3% (95%CI 0.6–2.0), respectively). Where possible, surgery should be delayed for at least 7 weeks following SARS-CoV-2 infection. Patients with ongoing symptoms ≥ 7 weeks from diagnosis may benefit from further delay.
eng
©2021 The Authors.Anaesthesiapublished by John Wiley & Sons Ltd on behalf of Association of Anaesthetists. This is an open access article under the terms of the Creative Commons Attribution-NonCommercial License, which permits use,distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
Sars-cov-2
COVID-19
Cirurgia
Mortalitat
Sars-cov-2
COVID-19
Cirugía
Mortalidad
Sars-cov-2
COVID-19
Surgery
Mortality
Timing of surgery following SARS-CoV-2 infection: an international prospective cohort study
info:eu-repo/semantics/article