2026-04-17T02:19:59Zhttps://recercat.cat/oai/request

oai:recercat.cat:20.500.12328/28802025-05-20T00:01:42Zcom_2072_67741col_2072_484352

00925njm 22002777a 4500 dc Ribas, Jesús author Valcárcel, Joana author Alba, Esther author Ruíz, Yolanda author Cuartero, Daniel author Iriarte, Adriana author Mora-Luján, José María author Huguet, Marta author Cerdà, Pau author Martínez-Yélamos, Sergio author Corbella Virós, Xavier author Santos, Salud author Riera-Mestre, Antoni author 2021 Background: Catheter-directed therapies (CDT) may be considered for selected patients with pulmonary embolism (PE); (2) Methods: Retrospective observational study including all consecutive patients with acute PE undergoing CDT (mechanical or pharmacomechanical) from January 2010 through December 2020. The aim was to evaluate in-hospital and long-term mortality and its predictive factors; (3) Results: We included 63 patients, 43 (68.3%) with high-risk PE. All patients underwent mechanical CDT and, additionally, 27 (43%) underwent catheter-directed thrombolysis. Twelve (19%) patients received failed systemic thrombolysis (ST) prior to CDT, and an inferior vena cava (IVC) filter was inserted in 28 (44.5%) patients. In-hospital PE-related and all-cause mortality rates were 31.7%; 95% CI 20.6–44.7% and 42.9%; 95% CI 30.5–56%, respectively. In multivariate analysis, age > 70 years and previous ST were strongly associated with PE-related and all-cause mortality, while IVC filter insertion during the CDT was associated with lower mortality rates. After a median follow-up of 40 (12–60) months, 11 more patients died (mortality rate of 60.3%; 95% CI 47.2–72.4%). Long-term survival was significantly higher in patients who received an IVC filter; (4) Conclusions: Age > 70 years and failure of previous ST were associated with mortality in acute PE patients treated with CDT. In-hospital and long-term mortality were lower in patients who received IVC filter insertion. Ribas, Jesús; Valcárcel, Joana; Alba, Esther [et al.]. Catheter-directed therapies in patients with pulmonary embolism: predictive factors of in-hospital mortality and long-term follow-up. Journal of Clinical Medicine, 2021, 10(20), 4716. Disponible en: <https://www.mdpi.com/2077-0383/10/20/4716>. Fecha de acceso: 22 oct. 2021. DOI: 10.3390/jcm10204716 2077-0383 http://hdl.handle.net/20.500.12328/2880 https://dx.doi.org/10.3390/jcm10204716 Procediments endovasculars Mortalitat Embòlia pulmonar Trombectomia Teràpia trombolítica Filtres de vena cava Procedimientos endovasculares Mortalidad Embolia pulmonar Trombectomía Terapia trombolítica Filtros de vena cava Endovascular procedures Mortality Pulmonary embolism Thrombectomy Thrombolytic therapy Vena cava filters Catheter-directed therapies in patients with pulmonary embolism: predictive factors of in-hospital mortality and long-term follow-up