2026-04-18T07:56:15Zhttps://recercat.cat/oai/request

oai:recercat.cat:20.500.12327/9312025-10-22T11:32:01Zcom_2072_4428com_2072_4427col_2072_487898

00925njm 22002777a 4500 dc Crespo-Piazuelo, Daniel author Criado-Mesas, Lourdes author Revilla, Manuel author Castelló, Anna author Noguera, José L. author Fernández, Ana I. author Ballester, Maria author Folch, Josep M. author 2020-08-18 Meat quality has an important genetic component and can be modified by the fatty acid (FA) composition and the amount of fat contained in adipose tissue and muscle. The present study aimed to find genomic regions associated with the FA composition in backfat and muscle (longissimus dorsi) in 439 pigs with three different genetic backgrounds but having the Iberian breed in common. Genome-wide association studies (GWAS) were performed between 38,424 single-nucleotide polymorphisms (SNPs) covering the pig genome and 60 phenotypic traits related to backfat and muscle FA composition. Nine significant associated regions were found in backfat on the Sus scrofa chromosomes (SSC): SSC1, SSC2, SSC4, SSC6, SSC8, SSC10, SSC12, and SSC16. For the intramuscular fat, six significant associated regions were identified on SSC4, SSC13, SSC14, and SSC17. A total of 52 candidate genes were proposed to explain the variation in backfat and muscle FA composition traits. GWAS were also reanalysed including SNPs on five candidate genes (ELOVL6, ELOVL7, FADS2, FASN, and SCD). Regions and molecular markers described in our study may be useful for meat quality selection of commercial pig breeds, although several polymorphisms were breed-specific, and further analysis would be needed to evaluate possible causal mutations. Crespo-Piazuelo, Daniel, Lourdes Criado-Mesas, Manuel Revilla, Anna Castelló, José L. Noguera, Ana I. Fernández, Maria Ballester, and Josep M. Folch. 2020. "Identification Of Strong Candidate Genes For Backfat And Intramuscular Fatty Acid Composition In Three Crosses Based On The Iberian Pig". Scientific Reports 10 (1). doi:10.1038/s41598-020-70894-2. 2045-2322 http://hdl.handle.net/20.500.12327/931 https://doi.org/10.1038/s41598-020-70894-2 Identification of strong candidate genes for backfat and intramuscular fatty acid composition in three crosses based on the Iberian pig