2026-04-13T00:09:43Zhttps://recercat.cat/oai/requestoai:recercat.cat:20.500.12327/31282025-10-22T11:27:17Zcom_2072_4428com_2072_4427col_2072_487898
RECERCAT
author
Duran-Montge, P.
author
Theil, P. K.
author
Lauridsen, C.
author
Esteve-Garcia, Enric
other
Producció Animal
group
Nutrició Animal
2025-10-22T11:27:17Z
2025-10-22T11:27:17Z
2009-01-01
Duran-Montgé, P., P. K. Theil, C. Lauridsen, and E. Esteve-Garcia. 2009. “Dietary Fat Source Affects Metabolism of Fatty Acids in Pigs as Evaluated by Altered Expression of Lipogenic Genes in Liver and Adipose Tissues.” Animal 3 (4): 535–542. doi: 10.1017/s1751731108003686
1751-7311
http://hdl.handle.net/20.500.12327/3128
https://doi.org/10.1017/S1751731108003686
Little is known about pig gene expressions related to dietary fatty acids (FAs) and most work have been conducted in rodents.
The aim of this study was to investigate how dietary fats regulate fat metabolism of pigs in different tissues. Fifty-six crossbred
gilts (62 6 5.2 kg BW) were fed one of seven dietary treatments (eight animals per treatment): a semi-synthetic diet containing
a very low level of fat (no fat (NF)) and six fat-supplemented diets (ca. 10%) based on barley and soybean meal. The
supplemental fat sources were tallow (T), high-oleic sunflower oil (HOSF), sunflower oil (SFO), linseed oil (LO), blend (FB) (55%
T, 35% SFO and 10% LO) and fish oil (FO) blend (40% FO and 60% LO). Pigs were slaughtered at 100 kg BW and autopsies
from liver, adipose tissue and muscle semimembranousus were collected for qPCR. The messenger ribonucleic acid (mRNA)
abundances of genes related to lipogenesis were modified due to dietary treatments in both liver (sterol regulatory elementbinding protein-1 (SREBP-1), acetyl CoA carboxylase (ACACA) and stearoyl CoA desaturase (SCD)) and adipose tissue (fatty acid
synthase (FASN), ACACA and SCD), but were not affected in semimembranousus muscle. In the liver, the mRNA abundances of
genes encoding lipogenic enzymes were highest in pigs fed HOSF and lowest in pigs fed FO. In adipose tissue, the mRNA
abundances were highest in pigs fed the NF diet and lowest in pigs fed T. The study demonstrated that dietary FAs stimulate
lipogenic enzyme gene expression differently in liver, fat and muscles tissues.
eng
Attribution-NonCommercial-NoDerivatives 4.0 International
Dietary fat source affects metabolism of fatty acids in pigs as evaluated by altered expression of lipogenic genes in liver and adipose tissues
info:eu-repo/semantics/article