2026-04-14T09:29:34Zhttps://recercat.cat/oai/request

oai:recercat.cat:20.500.12327/3112025-10-22T11:01:50Zcom_2072_4428com_2072_4427col_2072_487898

Comparison of vaccination protocols against Mycoplasma hyopneumoniae during the gilt acclimation period Garza-Moreno, Laura Pieters, Maria López-Soria, Sergio Carmona, Marta Krejci, Roman Segalés, Joaquim Sibila, Marina Producció Animal Sanitat Animal 619 This study evaluated different gilt vaccination protocols againstMycoplasma (M.) hyopneumoniaeat acclimationand their effect on the genetic diversity. A total of 180M. hyopneumoniaenaïve gilts were selected 1 week post-entry (wpe) at the acclimation barn in a clinically affectedM. hyopneumoniaefarm. Gilts were distributed ac-cording to theM. hyopneumoniaeantibodies levels into three different vaccination schedules: A) four doses of aM. hyopneumoniaecommercial vaccine at 2, 4, 6 and 8 wpe; B) two vaccine doses at 2 and 6 wpe and PBS at 4 and8 wpe; and C) four PBS doses at the same wpe. Detection ofM. hyopneumoniae(rt-PCR) and antibodies (ELISA)were assessed in gilts at 1, 14, 27 and 34 wpe and in 6 of their piglets at weaning. Rt-PCR positive gilts weredetected at 14 wpe, being the proportion significantly lower in groups A and B (3/120, 3%) than C (27/60, 45%).Seroconversion was detected at 14 wpe, showing significant differences in percentage of inhibition (PI) betweengroups A (median 4.9, range 3.1–19.9) and B (5.5, 3.7–13.5), and C (14.3, 3.3–53.2). Gilts remained seropositiveover the study and significant differences in PI were detected between groups A and B versus C. All piglets werert-PCR negative, but the proportion of seropositive piglets coming from vaccinated gilts was significantly higherthan the non-vaccinated group.M. hyopneumoniaecharacterization showed high variability. Hence, gilt vacci-nation with 2 or 4 doses significantly decreased the pathogen infectious pressure, variability, and provided highantibody levels to gilts and their offspring. info:eu-repo/semantics/acceptedVersion 2018-12-12 info:eu-repo/semantics/article Garza-Moreno, Laura, Maria Pieters, Sergio López-Soria, Marta Carmona, Roman Krejci, Joaquim Segalés, and Marina Sibila. 2019. "Comparison Of Vaccination Protocols Against Mycoplasma Hyopneumoniae During The Gilt Acclimation Period". Veterinary Microbiology 229: 7-13. Elsevier BV. doi:10.1016/j.vetmic.2018.12.005. 0378-1135 http://hdl.handle.net/20.500.12327/311 https://doi.org/10.1016/j.vetmic.2018.12.005 eng Veterinary Microbiology Attribution-NonCommercial-NoDerivatives 4.0 International http://creativecommons.org/licenses/by-nc-nd/4.0/ info:eu-repo/semantics/openAccess 32 Elsevier