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               <dc:title>Histopathological and virological findings in emaciated pigs from Mexico: an exploratory study</dc:title>
               <dc:creator>Alpízar, Aide</dc:creator>
               <dc:creator>Segalés, Joaquim</dc:creator>
               <dc:creator>Martínez, Simón</dc:creator>
               <dc:creator>Martínez, Atalo</dc:creator>
               <dc:creator>Socci, Guadalupe</dc:creator>
               <dc:creator>Córdova, Dionicio</dc:creator>
               <dc:creator>Fajardo, Raul</dc:creator>
               <dc:contributor>Producció Animal</dc:contributor>
               <dc:contributor>Sanitat Animal</dc:contributor>
               <dc:description>The objective of this work was to detect the presence of three main pig respiratory viral agents&#xd;
(porcine rubulavirus [PorPV], porcine circovirus type 2 [PCV-2], and porcine reproductive and&#xd;
respiratory syndrome virus [PRRSV]) in tissues of emaciated piglets from the Bajío Region&#xd;
(Mexico). Necropsies and histopathological studies of 37 pigs with poor body condition were&#xd;
performed; viruses were detected by molecular biology methods and PCV-2 was further assessed&#xd;
by immunohistochemistry (IHC). Histopathologically, interstitial pneumonia was observed in&#xd;
25/37 (68%) of the piglets. Also, a varying degree of lymphocyte depletion in lymphoid organs&#xd;
was found in 14/37 (38%) animals. Through polymerase chain reaction (PCR) and/or reverse&#xd;
transcription polymerase chain reaction (RT-PCR), from the 37 pigs, 16 were positive for PCV-2,&#xd;
18 for PRRSV and 1 for PorPV. In accordance with these results, the infection and/or co-infection&#xd;
with PCV-2 and PRRSV were fairly frequent findings in piglets with poor body condition in&#xd;
Mexico, while the infection by PorPV was apparently negligible. Wasting of post-weaning piglets&#xd;
is a global pig farming problem that causes great economic losses and has been associated with&#xd;
diverse factors: microbial agents, environmental factors, nutritional factors, and management.&#xd;
When the Blue Eye Disease was first reported in Mexico, it was associated with severe wasting&#xd;
in post-weaning piglets. This study demonstrated that this disease does not seem to play such an&#xd;
important role in the wasting as was previously thought.</dc:description>
               <dc:date>2025-10-22T11:21:49Z</dc:date>
               <dc:date>2025-10-22T11:21:49Z</dc:date>
               <dc:date>2018-06-27</dc:date>
               <dc:type>info:eu-repo/semantics/article</dc:type>
               <dc:identifier>Alpízar, Aide, Joaquim Segalés, Simón Martínez, Atalo Martínez, Guadalupe Socci, Dionicio Córdova, and Raul Fajardo. 2018. "Histopathological And Virological Findings In Emaciated Pigs From Mexico: An Exploratory Study". Acta Veterinaria Brno 87 (3): 213-217. University of Veterinary and Pharmaceutical Sciences. doi:10.2754/avb201887030213.</dc:identifier>
               <dc:identifier>0001-7213</dc:identifier>
               <dc:identifier>http://hdl.handle.net/20.500.12327/257</dc:identifier>
               <dc:identifier>https://doi.org/10.2754/avb201887030213</dc:identifier>
               <dc:language>eng</dc:language>
               <dc:relation>Acta Veterinaria Brno</dc:relation>
               <dc:rights>http://creativecommons.org/licenses/by/4.0/</dc:rights>
               <dc:rights>info:eu-repo/semantics/openAccess</dc:rights>
               <dc:rights>Attribution 4.0 International</dc:rights>
               <dc:publisher>University of Veterinary and Pharmaceutical Sciences, Brno</dc:publisher>
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