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oai:recercat.cat:20.500.12327/14982025-10-22T11:28:10Zcom_2072_4428com_2072_4427col_2072_487898
RECERCAT author EFSA Panel on Biological Hazards (BIOHAZ) author Koutsoumanis, Konstantinos author Allende, Ana author Alvarez-Ordóñez, Avelino author Bolton, Declan author Bover-Cid, Sara author Chemaly, Marianne author Davies, Robert author De Cesare, Alessandra author Herman, Lieve author Hilbert, Friederike author Lindqvist, Roland author Nauta, Maarten author Ru, Giuseppe author Simmons, Marion author Skandamis, Panagiotis author Suffredini, Elisabetta author Andersson, Dan I author Bampidis, Vasileios author Bengtsson-Palme, Johan author Bouchard, Damien author Ferran, Aude author Kouba, Maryline author López Puente, Secundino author López-Alonso, Marta author Nielsen, Søren Saxmose author Pechová, Alena author Petkova, Mariana author Girault, Sebastien author Broglia, Alessandro author Guerra, Beatriz author Innocenti, Matteo Lorenzo author Liébana, Ernesto author López-Gálvez, Gloria author Manini, Paola author Stella, Pietro author Peixe, Luisa other Indústries Alimentàries group Funcionalitat i Seguretat Alimentària 2025-10-22T11:28:10Z 2025-10-22T11:28:10Z 2021-10-26 Koutsoumanis, Konstantinos, Ana Allende, Avelino Alvarez‐Ordóñez, Declan Bolton, Sara Bover‐Cid, Marianne Chemaly, and Robert Davies et al. 2021. "Maximum Levels Of Cross‐Contamination For 24 Antimicrobial Active Substances In Non‐Target Feed. Part 3: Amprolium". EFSA Journal 19 (10). doi:10.2903/j.efsa.2021.6854. 1831-4732 http://hdl.handle.net/20.500.12327/1498 https://doi.org/10.2903/j.efsa.2021.6854 The specific concentrations of amprolium in non-target feed for food-producing animals, below which there would not be an effect on the emergence of, and/or selection for, resistance in bacteria relevant for human and animal health, as well as the specific antimicrobial concentrations in feed which have an effect in terms of growth promotion/increased yield were assessed by EFSA in collaboration with EMA. Details of the methodology used for this assessment, associated data gaps and uncertainties, are presented in a separate document. To address antimicrobial resistance, the Feed Antimicrobial Resistance Selection Concentration (FARSC) model developed specifically for the assessment was applied. However, due to the lack of data on the parameters required to calculate the FARSC for amprolium, it was not possible to conclude the assessment. To address growth promotion, data from scientific publications obtained from an extensive literature review were used. Levels of amprolium in feed that showed to have an effect on growth promotion/increased yield were reported. The lack of antibacterial activity at clinically relevant concentrations for amprolium suggests that further studies relating to bacterial resistance are not a priority. eng Attribution-NoDerivatives 4.0 International Maximum levels of cross-contamination for 24 antimicrobial active substances in non-target feed. Part 3: Amprolium info:eu-repo/semantics/article