2026-04-18T04:00:16Zhttps://recercat.cat/oai/request

oai:recercat.cat:11351/98572025-10-24T08:28:30Zcom_2072_451660com_2072_378040col_2072_451662

Do cross-food allergies to propofol exist? Espinós Ramírez, Carles PEIG-FONT, ANNA Gil Esteller, Paula Castillo Marchuet, María José Martinez García, Maria VIÑAS DOMINGO, MARTA Saura Foix, María del Pilar [Espinós Ramírez C, Peig Font A, Gil Esteller P, Martinez García M] Servei d’Anestesiologia, Hospital de Terrassa, Consorci Sanitari de Terrassa, Terrassa, Spain. Universitat Internacional de Catalunya, Barcelona, Spain. [Viñas Domingo M, Castillo Marchuet MJ, Saura Foix MP] Servei d’Anestesiologia, Hospital de Terrassa, Consorci Sanitari de Terrassa, Terrassa, Spain Consorci Sanitari de Terrassa Propofol Al·lèrgia alimentària CHEMICALS AND DRUGS::Organic Chemicals::Hydrocarbons::Hydrocarbons, Cyclic::Hydrocarbons, Aromatic::Benzene Derivatives::Phenols::Propofol DISEASES::Immune System Diseases::Hypersensitivity::Hypersensitivity, Immediate::Food Hypersensitivity COMPUESTOS QUÍMICOS Y DROGAS::compuestos orgánicos::hidrocarburos::hidrocarburos cíclicos::hidrocarburos aromáticos::derivados del benceno::fenoles::propofol ENFERMEDADES::enfermedades del sistema inmune::hipersensibilidad::hipersensibilidad inmediata::hipersensibilidad a los alimentos Alergia a la comida; Sensibilización alimentaria; Propofol Food allergy; Food sensitization; Propofol Al·lèrgia alimentària; Sensibilització alimentària; Propofol Background: Propofol is a short and rapidly acting intravenous anesthetic extensively used for the induction and maintenance of general anesthesia. It is a lipid emulsion that contains soybean oil, purified egg phosphatide, and egg lecithin. Therefore, the package leaflet indicates that its administration is contraindicated in patients allergic to soy, eggs, or peanuts. Our study aimed to determine whether patients with proven food allergies are allergic to propofol. Methods: Patients of all ages allergic to soy, eggs, or peanuts who agreed to undergo skin testing for propofol allergies were included. The subjects first underwent a skin test to confirm food allergies. If candidates were negative, they were excluded. If the result was positive, a propofol skin test was performed. Results: Sixty-four patients with confirmed food allergies underwent a propofol skin test. Only one was positive in the propofol skin test (1.6%). The patient was allergic to peanuts and soybeans. These results reinforce the idea that there is no justification for avoiding propofol use in these subjects. Conclusions: Propofol can be safely administered to patients allergic to soy, eggs, or peanuts. We recommend caution in patients with a history of anaphylaxis after ingestion of the above-mentioned foods. 2023-06-22T10:04:19Z 2023-06-22T10:04:19Z 2022-10 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Espinós Ramírez C, Viñas Domingo M, Peig Font A, Gil Esteller P, Castillo Marchuet MJ, Saura Foix MP, et al. Do cross-food allergies to propofol exist?. Anesth Pain Med. 2022 Oct;17(4):381-85. 2383-7977 https://hdl.handle.net/11351/9857 10.17085/apm.22195 36317430 http://hdl.handle.net/11351/9857 eng Anesthesia and Pain Medicine;17(4) https://doi.org/10.17085/apm.22195 Attribution-NonCommercial 4.0 International http://creativecommons.org/licenses/by-nc/4.0/ info:eu-repo/semantics/openAccess application/pdf Korean Society of Anesthesiologists Scientia