2026-04-17T02:33:49Zhttps://recercat.cat/oai/request

oai:recercat.cat:11351/95842024-06-06T13:55:12Zcom_2072_378070com_2072_378040col_2072_378092

00925njm 22002777a 4500 dc Dramburg, Stephanie author Hilger, Christiane author Santos, Alexandra author de las Vecillas Sanchez, Leticia author Aalberse, Rob author Acevedo, Nathalie author Luengo Sánchez, Olga author 2023-05-22T12:33:54Z 2023-05-22T12:33:54Z 2023-03 Alergia; Anafilaxia; Asma Allergy; Anaphylaxis; Asthma Al·lèrgia; Anafilaxi; Asma Since the discovery of immunoglobulin E (IgE) as a mediator of allergic diseases in 1967, our knowledge about the immunological mechanisms of IgE-mediated allergies has remarkably increased. In addition to understanding the immune response and clinical symptoms, allergy diagnosis and management depend strongly on the precise identification of the elicitors of the IgE-mediated allergic reaction. In the past four decades, innovations in bioscience and technology have facilitated the identification and production of well-defined, highly pure molecules for component-resolved diagnosis (CRD), allowing a personalized diagnosis and management of the allergic disease for individual patients. The first edition of the “EAACI Molecular Allergology User's Guide” (MAUG) in 2016 rapidly became a key reference for clinicians, scientists, and interested readers with a background in allergology, immunology, biology, and medicine. Nevertheless, the field of molecular allergology is moving fast, and after 6 years, a new EAACI Taskforce was established to provide an updated document. The Molecular Allergology User's Guide 2.0 summarizes state-of-the-art information on allergen molecules, their clinical relevance, and their application in diagnostic algorithms for clinical practice. It is designed for both, clinicians and scientists, guiding health care professionals through the overwhelming list of different allergen molecules available for testing. Further, it provides diagnostic algorithms on the clinical relevance of allergenic molecules and gives an overview of their biology, the basic mechanisms of test formats, and the application of tests to measure allergen exposure. Al·lèrgia - Tractament Al·lèrgia - Diagnòstic Immunoglobulina E DISEASES::Immune System Diseases::Hypersensitivity Other subheadings::Other subheadings::/therapy CHEMICALS AND DRUGS::Amino Acids, Peptides, and Proteins::Proteins::Blood Proteins::Immunoproteins::Immunoglobulins::Antibodies::Immunoglobulin Isotypes::Immunoglobulin E ENFERMEDADES::enfermedades del sistema inmune::hipersensibilidad Otros calificadores::Otros calificadores::/terapia COMPUESTOS QUÍMICOS Y DROGAS::aminoácidos, péptidos y proteínas::proteínas::proteínas sanguíneas::inmunoproteínas::inmunoglobulinas::anticuerpos::isotipos de inmunoglobulinas::inmunoglobulina E EAACI Molecular Allergology User's Guide 2.0