2026-04-17T18:01:34Zhttps://recercat.cat/oai/request

oai:recercat.cat:11351/91842025-10-24T10:44:19Zcom_2072_378070com_2072_378040col_2072_378092

Latin American anaphylaxis registry Jares, Edgardo Cardona Dahl, Victòria Gomez, R Maximiliano Rosario Filho, Nelson Augusto Cherrez Ojeda, Ivan Bernstein, Jonathan Institut Català de la Salut [Jares EJ] Allergy Section, CMP S.A. LIBRA Foundation. Buenos Aires, Argentina. [Cardona V] Servei d’Al·lergologia, Vall d'Hebron Hospital Universitari, Barcelona, Spain. [Gómez RM] School of Health Sciences, Catholic University of Salta, Argentina. [Bernstein JA] Professor of Medicine University of Cincinnati, Department of Internal Medicine, Division of Rheumatology, Allergy and Immunology. Cincinnati, USA. [Rosario Filho NA] Professor of Pediatrics, Federal University of Parana, Brazil. [Cherrez-Ojeda I] Respiralab Research Center, Universidad Espiritu Santo, Samborondon, Ecuador Vall d'Hebron Barcelona Hospital Campus Anafilaxi Al·lèrgia als medicaments Registres mèdics DISEASES::Immune System Diseases::Hypersensitivity::Hypersensitivity, Immediate::Anaphylaxis DISEASES::Chemically-Induced Disorders::Drug-Related Side Effects and Adverse Reactions::Drug Hypersensitivity PUBLIC HEALTH::Epidemiology and Biostatistics::Biostatistics::Information Storage and Retrieval::Diseases Registries ENFERMEDADES::enfermedades del sistema inmune::hipersensibilidad::hipersensibilidad inmediata::anafilaxia ENFERMEDADES::trastornos inducidos químicamente::efectos colaterales y reacciones adversas relacionados con medicamentos::hipersensibilidad medicamentosa SALUD PÚBLICA::epidemiología y bioestadística::bioestadística::almacenamiento y recuperación de la información::registros de enfermedades Anaphylaxis; Food hypersensitivity; Latin America Anafilaxi; Hipersensibilitat alimentària; Amèrica Llatina Anafilaxia; Hipersensibilidad alimentaria; América Latina Background Recent data about clinical features, triggers and management of anaphylaxis in Latin America is lacking. Objective To provide updated and extended data on anaphylaxis in this region. Method An online questionnaire was used, with 67 allergy units involved from 12 Latin-American countries and Spain. Among data recorded, demographic information, clinical features, severity, triggering agents, and treatment were received. Results Eight hundred and seventeen anaphylactic reactions were recorded. No difference in severity, regardless of pre-existing allergy or asthma history was found. Drug induced anaphylaxis (DIA) was most frequent (40.6%), followed by food induced anaphylaxis (FIA) (32.9%) and venom induced anaphylaxis (VIA) (12%). FIA and VIA were more common in children-adolescents. Non-steroidal anti-inflammatory drugs (NSAIDs) and beta-lactam antibiotics (BLA) were the most frequent drugs involved. Milk (61.1% of FIA) and egg (15.4% of FIA) in children, and shellfish (25.5% of FIA), fresh fruits (14.2% of FIA), and fish (11.3% of FIA) in adults were the most common FIA triggers. Fire ants were the most frequent insect triggers, and they induced more severe reactions than triggers of FIA and DIA (p < 0.0001). Epinephrine was used in 43.8% of anaphylaxis episodes. After Emergency Department treatment, epinephrine was prescribed to 13% of patients. Conclusions Drugs (NSAIDs and BLA), foods (milk and egg in children and shellfish, fruits and fish in adults) and fire ants were the most common inducers of anaphylaxis. Epinephrine was used in less than half of the episodes emphasizing the urgent need to improve dissemination and implementation of anaphylaxis guidelines. 2023-03-16T11:14:45Z 2023-03-16T11:14:45Z 2023-02 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Jares EJ, Cardona V, Gómez RM, Bernstein JA, Rosario Filho NA, Cherrez-Ojeda I, et al. Latin American anaphylaxis registry. World Allergy Organ J. 2023 Feb;16(2):100748. 1939-4551 https://hdl.handle.net/11351/9184 10.1016/j.waojou.2023.100748 36816598 000940322200001 http://hdl.handle.net/11351/9184 eng World Allergy Organization Journal;16(2) https://doi.org/10.1016/j.waojou.2023.100748 Attribution-NonCommercial-NoDerivatives 4.0 International http://creativecommons.org/licenses/by-nc-nd/4.0/ info:eu-repo/semantics/openAccess application/pdf Elsevier Scientia