2026-04-13T22:45:35Zhttps://recercat.cat/oai/request

oai:recercat.cat:11351/91342025-10-24T10:18:42Zcom_2072_378070com_2072_378040col_2072_378092

Diagnostic workup of childhood interstitial lung disease Nathan, Nadia Michel, Katarzyna Emiralioglu, Nagehan Torrent Vernetta, Alba Griese, Matthias Carlens, Julia Gilbert, Carlee Institut Català de la Salut [Nathan N] AP-HP, Sorbonne Université, Pediatric Pulmonology Department and Reference Center for Rare Lung Disease RespiRare, Armand Trousseau Hospital, Paris, France. Sorbonne Université, Inserm Laboratory of Childhood Genetic Diseases, Armand Trousseau Hospital, Paris, France. [Griese M, Michel K] Department of Paediatric Pneumology, Dr von Hauner Children’s Hospital, German Centre for Lung Research, University of Munich, Munich, Germany. [Carlens J] Clinic for Pediatric Pneumology, Hannover Medical School, Hannover, Germany. [Gilbert C] Institute of Population Health, University of Liverpool, Liverpool, UK. [Emiralioglu N] Department of Pediatric Pulmonology, Hacettepe University Faculty of Medicine, Ankara, Turkey. [Torrent-Vernetta A] Unitat de Pneumologia Pediàtrica i Fibrosi Quística, Servei de Pediatria, Vall d’Hebron Hospital Universitari, Barcelona, Spain. Universitat Autònoma de Barcelona, Bellaterra, Spain. Centro de Investigación Biomédica en Red de Enfermedades Raras (CIBERER), Instituto de Salud Carlos III (ISCIII), Madrid, Spain Vall d'Hebron Barcelona Hospital Campus Pulmons - Càncer - Diagnòstic Imatgeria per al diagnòstic Rentada broncoalveolar Infants DISEASES::Respiratory Tract Diseases::Lung Diseases::Lung Diseases, Interstitial Other subheadings::Other subheadings::/diagnosis ANALYTICAL, DIAGNOSTIC AND THERAPEUTIC TECHNIQUES, AND EQUIPMENT::Diagnosis::Diagnostic Techniques and Procedures::Diagnostic Imaging ANALYTICAL, DIAGNOSTIC AND THERAPEUTIC TECHNIQUES, AND EQUIPMENT::Investigative Techniques::Therapeutic Irrigation::Bronchoalveolar Lavage NAMED GROUPS::Persons::Age Groups::Child ENFERMEDADES::enfermedades respiratorias::enfermedades pulmonares::enfermedades pulmonares intersticiales Otros calificadores::Otros calificadores::/diagnóstico TÉCNICAS Y EQUIPOS ANALÍTICOS, DIAGNÓSTICOS Y TERAPÉUTICOS::diagnóstico::técnicas y procedimientos diagnósticos::diagnóstico por imagen TÉCNICAS Y EQUIPOS ANALÍTICOS, DIAGNÓSTICOS Y TERAPÉUTICOS::técnicas de investigación::irrigación terapéutica::lavado broncoalveolar DENOMINACIONES DE GRUPOS::personas::Grupos de Edad::niño Interstitial and orphan lung disease Enfermedad pulmonar intersticial y huérfana Malaltia pulmonar intersticial i orfe Childhood interstitial lung diseases (chILDs) are rare and heterogeneous diseases with significant morbidity and mortality. An accurate and quick aetiological diagnosis may contribute to better management and personalised treatment. On behalf of the European Respiratory Society Clinical Research Collaboration for chILD (ERS CRC chILD-EU), this review summarises the roles of the general paediatrician, paediatric pulmonologists and expert centres in the complex diagnostic workup. Each patient's aetiological chILD diagnosis must be reached without prolonged delays in a stepwise approach from medical history, signs, symptoms, clinical tests and imaging, to advanced genetic analysis and specialised procedures including bronchoalveolar lavage and biopsy, if necessary. Finally, as medical progress is fast, the need to revisit a diagnosis of “undefined chILD” is stressed. 2023-03-09T10:55:07Z 2023-03-09T10:55:07Z 2023-03-31 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Nathan N, Griese M, Michel K, Carlens J, Gilbert C, Emiralioglu N, et al. Diagnostic workup of childhood interstitial lung disease. Eur Respir Rev. 2023 Mar 31;32(167):220188. 1600-0617 https://hdl.handle.net/11351/9134 10.1183/16000617.0188-2022 36813289 http://hdl.handle.net/11351/9134 eng European Respiratory Review;32(167) https://doi.org/10.1183/16000617.0188-2022 Attribution-NonCommercial 4.0 International http://creativecommons.org/licenses/by-nc/4.0/ info:eu-repo/semantics/openAccess application/pdf European Respiratory Society Scientia