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oai:recercat.cat:11351/90792025-10-24T10:23:59Zcom_2072_378070com_2072_378040col_2072_378092

Molecular Diagnosis of Endemic Mycoses Valero, Clara Martin Gomez, M Teresa Buitrago, María José Institut Català de la Salut [Valero C] Manchester Fungal Infection Group, Division of Evolution, Infection, and Genomics, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK. [Martín-Gómez MT] Servei de Microbiologia, Vall d’Hebron Hospital Universitari, Barcelona, Spain. [Buitrago MJ] Mycology Reference Laboratory, Centro Nacional de Microbiología, Instituto de Salud Carlos III, Majadahonda, Madrid, Spain. CIBERINFEC, ISCIII-CIBER de Enfermedades Infecciosas, Instituto de Salud Carlos III, Majadahonda, Madrid, Spain Vall d'Hebron Barcelona Hospital Campus Micosi - Diagnòstic molecular DISEASES::Bacterial Infections and Mycoses::Mycoses Other subheadings::Other subheadings::/diagnosis ANALYTICAL, DIAGNOSTIC AND THERAPEUTIC TECHNIQUES, AND EQUIPMENT::Diagnosis::Diagnostic Techniques and Procedures::Clinical Laboratory Techniques::Molecular Diagnostic Techniques ENFERMEDADES::infecciones bacterianas y micosis::micosis Otros calificadores::Otros calificadores::/diagnóstico TÉCNICAS Y EQUIPOS ANALÍTICOS, DIAGNÓSTICOS Y TERAPÉUTICOS::diagnóstico::técnicas y procedimientos diagnósticos::técnicas de laboratorio clínico::técnicas de diagnóstico molecular Endemic mycoses; Molecular diagnosis Micosis endémicas; Diagnóstico molecular Micosis endèmiques; Diagnòstic molecular Diagnosis of endemic mycoses is still challenging. The moderated availability of reliable diagnostic methods, the lack of clinical suspicion out of endemic areas and the limitations of conventional techniques result in a late diagnosis that, in turn, delays the implementation of the correct antifungal therapy. In recent years, molecular methods have emerged as promising tools for the rapid diagnosis of endemic mycoses. However, the absence of a consensus among laboratories and the reduced availability of commercial tests compromises the diagnostic effectiveness of these methods. In this review, we summarize the advantages and limitations of molecular methods for the diagnosis of endemic mycoses. This research was funded by research project PI21CIII/00007 from Spanish Fondo de Investigaciones Sanitarias of the Instituto de Salud Carlos III. 2023-03-01T11:29:00Z 2023-03-01T11:29:00Z 2022-12-30 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Valero C, Martín-Gómez MT, Buitrago MJ. Molecular Diagnosis of Endemic Mycoses. J Fungi. 2022 Dec 30;9(1):59. 2309-608X https://hdl.handle.net/11351/9079 10.3390/jof9010059 36675880 000915185000001 http://hdl.handle.net/11351/9079 eng Journal of Fungi;9(1) https://doi.org/10.3390/jof9010059 Attribution 4.0 International http://creativecommons.org/licenses/by/4.0/ info:eu-repo/semantics/openAccess application/pdf MDPI Scientia