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oai:recercat.cat:11351/88602025-10-24T10:32:50Zcom_2072_378070com_2072_378040col_2072_378092

Cryotherapy in the paediatric airway: Indications, success and safety Schramm, Dirk Freitag, Nadine Kötz, Karsten Iglesias Serrano, Ignacio Koblizek, Vladimir Culebras Amigo, Mario Institut Català de la Salut [Schramm D, Freitag N] Department of General Pediatrics, Neonatology and Pediatric Cardiology, Medical Faculty, University Hospital Düsseldorf, Heinrich-Heine-University Düsseldorf, Düsseldorf, Germany. [Kötz K] Queen Silvias Children Hospital, Sahlgrenska University Hospital, Gothenburg, Sweden. [Iglesias-Serrano I] Unitat de Pneumologia Pediàtrica i Fibrosi Quística, Vall d’Hebron Hospital Universitari, Barcelona, Spain. [Culebras-Amigo M] Servei de Pneumologia, Vall d’Hebron Hospital Universitari, Barcelona, Spain. [Koblizek V] Department of Pneumology, University Hospital Hradec Kralove, Faculty of Medicine in Hradec Kralove, Charles University, Prague, Czechia Vall d'Hebron Barcelona Hospital Campus Bronquis Broncoscòpia Fred - Ús terapèutic Infants ANALYTICAL, DIAGNOSTIC AND THERAPEUTIC TECHNIQUES, AND EQUIPMENT::Therapeutics::Cryotherapy ANALYTICAL, DIAGNOSTIC AND THERAPEUTIC TECHNIQUES, AND EQUIPMENT::Diagnosis::Diagnostic Techniques and Procedures::Diagnostic Techniques, Respiratory System::Bronchoscopy NAMED GROUPS::Persons::Age Groups::Child ANATOMY::Respiratory System::Lung::Bronchi TÉCNICAS Y EQUIPOS ANALÍTICOS, DIAGNÓSTICOS Y TERAPÉUTICOS::terapéutica::crioterapia TÉCNICAS Y EQUIPOS ANALÍTICOS, DIAGNÓSTICOS Y TERAPÉUTICOS::diagnóstico::técnicas y procedimientos diagnósticos::técnicas diagnósticas respiratorias::broncoscopia DENOMINACIONES DE GRUPOS::personas::Grupos de Edad::niño ANATOMÍA::sistema respiratorio::pulmón::bronquios Airway obstruction; Cryobiopsy; Paediatric bronchoscopy Obstrucción de las vías respiratorias; Criobiopsia; Broncoscopia pediátrica Obstrucció de les vies respiratòries; Criobiòpsia; Broncoscòpia pediàtrica Background and objective Cryotherapy in interventional bronchoscopy is a new treatment modality, which has recently been made available for the paediatric airway. Lack of experience and safety concerns have led to hesitant adaptation. The aim of this study was to assess indications, success rates and complications of airway cryotherapy in children. Methods Bronchoscopists from medical centre performing cryotherapy in patients between 0 and 18 years were invited to participate in a prospective study based on an online questionnaire. Patient and participant data were collected between June 2020 and June 2021. Results A total of 69 cryotherapy procedures were performed in 57 patients a for three main indications: Biopsy (30), restoration of airway patency (23) and foreign body aspiration (16). The overall success rate was 93%, the remaining 7% were performed for foreign body removal and required a switch of technique. Restoration of airway patency was successfully applied in various pathologies, including mucus plugs, bronchial casts and post traumatic stenosis. The diagnostic yield of transbronchial biopsies was 96%. No severe complications were encountered; one pneumothorax following a cryobiopsy required a chest drain for 48 h. No child was admitted to intensive care or died from a procedural complication. Conclusion In this largest paediatric case collection to date, cryotherapy was safe and carried a high success rate. Cryobiopsy compares favourably to the widely used forceps biopsy and could replace it in the future. Paediatric bronchoscopists are encouraged to add cryotherapy to their armamentarium of airway interventions. Open Access funding enabled and organized by Projekt DEAL. 2023-01-17T07:23:57Z 2023-01-17T07:23:57Z 2022-11 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Schramm D, Freitag N, Kötz K, Iglesias-Serrano I, Culebras-Amigo M, Koblizek V, et al. Cryotherapy in the paediatric airway: Indications, success and safety. Respirology. 2022 Nov;27(11):966-74. 1440-1843 https://hdl.handle.net/11351/8860 10.1111/resp.14353 36054726 000846775700001 http://hdl.handle.net/11351/8860 eng Respirology;27(11) https://doi.org/10.1111/resp.14353 Attribution-NonCommercial 4.0 International http://creativecommons.org/licenses/by-nc/4.0/ info:eu-repo/semantics/openAccess application/pdf Wiley Scientia