2026-04-17T12:56:21Zhttps://recercat.cat/oai/request

oai:recercat.cat:11351/85432024-12-13T10:56:05Zcom_2072_378071com_2072_378040col_2072_378097

COVID-19 infection and renal injury: where is the place for acute interstitial nephritis disease? León Román, Juan Agraz Pamplona, Irene Vergara Arana, Ander Toapanta Gaibor, Nestor Gabriel García Carro, Clara Gabaldon Dominguez, Alejandra Roxana Bury Macias, Roxana Paola Bermejo Garcia, Sheila Bestard Matamoros, Oriol Soler Romeo, Maria Jose Ramos Terrades, Natalia Institut Català de la Salut [León-Román J, Agraz I, Vergara A, Ramos N, Toapanta N, Bury R, Bermejo S] Servei de Nefrologia, Vall d’Hebron Hospital Universitari, Barcelona, Spain. [García-Carro C] Clinico San Carlos University Hospital, Department of Nephrology, Madrid, Spain. [Gabaldón A] Servei d’Anatomia Patològica, Vall d’Hebron Hospital Universitari, Barcelona, Spain. [Bestard O] Servei de Nefrologia, Vall d’Hebron Hospital Universitari, Barcelona, Spain. Grup de Recerca en Nefrologia i Trasplantament Renal, Vall d’Hebron Institut de Recerca (VHIR), Barcelona, Spain. [Soler MJ] Servei de Nefrologia, Vall d’Hebron Hospital Universitari, Barcelona, Spain. Grup de Recerca en Nefrologia i Trasplantament Renal, Vall d’Hebron Institut de Recerca (VHIR), Barcelona, Spain. Red de Investigación Renal (REDINREN), Instituto Carlos IIIFEDER, Madrid, Spain Vall d'Hebron Barcelona Hospital Campus COVID-19 (Malaltia) Ronyons - Malalties DISEASES::Male Urogenital Diseases::Urologic Diseases::Kidney Diseases::Renal Insufficiency::Acute Kidney Injury DISEASES::Virus Diseases::RNA Virus Infections::Nidovirales Infections::Coronaviridae Infections::Coronavirus Infections ENFERMEDADES::enfermedades urogenitales masculinas::enfermedades urológicas::enfermedades renales::insuficiencia renal::lesión renal aguda ENFERMEDADES::virosis::infecciones por virus ARN::infecciones por Nidovirales::infecciones por Coronaviridae::infecciones por Coronavirus COVID-19; Nefritis tubulointersticial aguda; Biòpsia de ronyó COVID-19; Nefritis tubulointersticial aguda; Biopsia de riñón COVID-19; Acute tubulointerstitial nephritis; Kidney biopsy Novel coronavirus disease infection (coronavirus disease 2019, COVID-19) was declared a global pandemic in March 2020 and since then has become a major public health problem. The prevalence of COVID-19 infection and acute kidney injury (AKI) is variable depending on several factors such as race/ethnicity and severity of illness. The pathophysiology of renal involvement in COVID-19 infection is not entirely clear, but it could be in part explained by the viral tropism in the kidney parenchyma. AKI in COVID-19 infection can be either by direct invasion of the virus or as a consequence of immunologic response. Diverse studies have focused on the effect of COVID-19 on glomerulonephritis (GN) patients or the ‘novo’ GN; however, the effect of COVID-19 in acute tubulointerstitial nephritis (ATIN) has been scarcely studied. In this article, we present five cases with different spectrums of COVID-19 infection and ATIN that may suggest that recent diagnosis of ATIN is accompanied by a worse clinical prognosis in comparison with long-term diagnosed ATIN. This research was funded by ISCIIII-FEDER and ISCIII-RETICS REDinREN, grant number PI17/00257, PI21/01292, RD16/0009/0030, and RICORS RD21/0005/0016. Enfermedad Glomerular Compleja del Sistema Nacional de Salud (CSUR), enfermedades glomerulares complejas. 2022-11-28T11:34:26Z 2022-11-28T11:34:26Z 2022-09 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion León-Román J, Agraz I, Vergara A, Ramos N, Toapanta N, García-Carro C, et al. COVID-19 infection and renal injury: where is the place for acute interstitial nephritis disease?. Clin Kidney J. 2022 Sep;15(9):1698–1704. 2048-8513 https://hdl.handle.net/11351/8543 10.1093/ckj/sfac079 35999963 000768463100001 http://hdl.handle.net/11351/8543 eng Clinical Kidney Journal;15(9) https://doi.org/10.1093/ckj/sfac079 info:eu-repo/grantAgreement/ES/PE2017-2020/PI21%2F01292 info:eu-repo/grantAgreement/ES/PE2013-2016/RD16%2F0009%2F0030 info:eu-repo/grantAgreement/ES/PE2017-2020/RD21%2F0005%2F0016 Attribution-NonCommercial 4.0 International http://creativecommons.org/licenses/by-nc/4.0/ info:eu-repo/semantics/openAccess application/pdf Oxford University Press Scientia