2026-04-13T07:19:37Zhttps://recercat.cat/oai/request

oai:recercat.cat:11351/82662025-10-24T10:18:29Zcom_2072_378070com_2072_378040col_2072_378092

00925njm 22002777a 4500 dc García Fernández, Alba Estela author Barquin Del Pino, Raquel author Martinez, Mariano author Ferrer Costa, Roser author Casis Saenz, Ernesto author Xu, Clarke author 2022-10-06T12:05:38Z 2022-10-06T12:05:38Z 2022-08 Acute kidney injury; Creatinine; Point-of-care Lesión renal aguda; Creatinina; Punto de atención Lesió renal aguda; Creatinina; Punt d'atenció Background and aims GEM Premier ChemSTAT is a new point-of-care system providing rapid creatinine, BUN and tCO2 measurements together with electrolytes, metabolites, hematocrit, pH and pCO2 from a single whole blood specimen in acute care settings such as emergency departments and intensive care units. Accurate measurements of whole blood creatinine can aid in the diagnosis and treatment of renal diseases. Materials and methods Heparinized whole blood samples from different clinical locations were evaluated on the GEM Premier ChemSTAT and results compared to plasma from the same samples on the Beckman AU5800 or whole blood on the GEM Premier 4000. Precision studies were conducted with whole blood and quality control material. Results ChemSTAT correlated well with plasma samples on the AU5800 (regression slopes (S): 0.957–1.159, correlation coefficients (r)≥0.952) and with whole blood specimens on the GEM Premier 4000 (S: 0.9646–1.124, r ≥ 0.974). The repeatability was 0.1%–3.1% and QC precision were within lab and manufacturers’ specifications. Conclusion ChemSTAT demonstrated strong correlation to the comparative methods and excellent precision. Combining with its continuous quality management, ChemSTAT is suitable for acute care settings to provide rapid, reliable results, which could minimize time-to-treatment and improve patient outcome. http://hdl.handle.net/11351/8266 Ronyons - Malalties - Diagnòstic Creatinina Ronyons - Malalties - Tractament DISEASES::Male Urogenital Diseases::Urologic Diseases::Kidney Diseases Other subheadings::Other subheadings::Other subheadings::/complications CHEMICALS AND DRUGS::Heterocyclic Compounds::Heterocyclic Compounds, 1-Ring::Azoles::Imidazoles::Creatinine Other subheadings::Other subheadings::Other subheadings::/blood ENFERMEDADES::enfermedades urogenitales masculinas::enfermedades urológicas::enfermedades renales Otros calificadores::Otros calificadores::Otros calificadores::/complicaciones COMPUESTOS QUÍMICOS Y DROGAS::compuestos heterocíclicos::compuestos heterocíclicos de 1 anillo::azoles::imidazoles::creatinina Otros calificadores::Otros calificadores::Otros calificadores::/sangre Performance evaluation of a point of care cartridge of the new GEM Premier ChemSTAT analyzer