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Morphological Description of Frontal EEG Interictal and Ictal Discharges in an Adult Cohort of 175 Patients García-López, Beatriz Sueiras Gil, Maria Gómez-Menéndez, Ana Isabel Vázquez-Sánchez, Fernando Lloria-Gil, María Carmen González-Bernal, Jerónimo J. Institut Català de la Salut [García-López B, Gómez-Menéndez AI, Lloria-Gil MC] Neurophysiology Department, Burgos University Hospital, 09006 Burgos, Spain. [Sueiras-Gil M] Servei de Neurofisiologia, Vall d’Hebron Hospital Universitari, Barcelona, Spain. [Vázquez-Sánchez F] Neurology Department, Burgos University Hospital, 09006 Burgos, Spain. [Lloria-Gil MC] Department of Health Sciences, University of Burgos, 09001 Burgos, Spain Vall d'Hebron Barcelona Hospital Campus Epilèpsia del lòbul frontal Electroencefalografia Convulsions DISEASES::Nervous System Diseases::Central Nervous System Diseases::Brain Diseases::Epilepsy::Epilepsies, Partial::Epilepsy, Frontal Lobe ANALYTICAL, DIAGNOSTIC AND THERAPEUTIC TECHNIQUES, AND EQUIPMENT::Diagnosis::Diagnostic Techniques and Procedures::Diagnostic Techniques, Neurological::Electroencephalography DISEASES::Nervous System Diseases::Neurologic Manifestations::Seizures Other subheadings::Other subheadings::Other subheadings::/physiopathology ENFERMEDADES::enfermedades del sistema nervioso::enfermedades del sistema nervioso central::enfermedades cerebrales::epilepsia::epilepsias parciales::epilepsia del lóbulo frontal TÉCNICAS Y EQUIPOS ANALÍTICOS, DIAGNÓSTICOS Y TERAPÉUTICOS::diagnóstico::técnicas y procedimientos diagnósticos::técnicas diagnósticas neurológicas::electroencefalografía ENFERMEDADES::enfermedades del sistema nervioso::manifestaciones neurológicas::convulsiones Otros calificadores::Otros calificadores::Otros calificadores::/fisiopatología EEG morphology; Electroencephalography; Frontal lobe seizures Morfología EEG; Electroencefalografía; Convulsiones del lóbulo frontal Morfologia EEG; Electroencefalografia; Convulsions del lòbul frontal Clinical and electroencephalogram (EEG) features in frontal lobe epilepsy (FLE) vary considerably among patients, making the diagnosis a challenge. The objective of this study was to describe interictal and ictal EEG activity, identifying variables that could help to differentiate and diagnose frontal lobe epilepsy cases. A prospective cross-sectional study from patients with frontal interictal epileptiform discharges (IED) referred to the Vall d’Hebron University Hospital (Barcelona, Spain) after a clinical event compatible with epileptic seizures was designed. The interictal and ictal activity were analyzed to provide a detailed EEG description of the cases, using different statistical analyses. The morphological seizure pattern at the ictal onset remained globally unchanged over time in seizures arising from the frontal lobe for each patient. Isolated sharp waves were the most frequent waveforms in the expression of IED. Frontal lobe seizures are frequently short and sometimes appear grouped in clusters within the same recording. Often the ictal expression of the electrical activity in frontal lobe seizure is subtle and challenging to interpret. A description of the main findings is summarized to identify seizures arising from the frontal lobe and avoid false negatives findings in EEG interpretations. This research received no external funding. 2022-05-02T13:08:54Z 2022-05-02T13:08:54Z 2021-03 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion García-López B, Sueiras-Gil M, Gómez-Menéndez AI, Vázquez-Sánchez F, Lloria-Gil MC, González-Bernal JJ, et al. Morphological Description of Frontal EEG Interictal and Ictal Discharges in an Adult Cohort of 175 Patients. J Clin Med. 2021 Mar 15;10(6):1219. 2077-0383 https://hdl.handle.net/11351/7450 10.3390/jcm10061219 33804106 000651952300001 http://hdl.handle.net/11351/7450 eng Journal of Clinical Medicine;10(6) https://doi.org/10.3390/jcm10061219 Attribution 4.0 International http://creativecommons.org/licenses/by/4.0/ info:eu-repo/semantics/openAccess application/pdf MDPI Scientia