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oai:recercat.cat:11351/66682025-11-27T07:36:51Zcom_2072_451669com_2072_378040col_2072_451670

The Longitudinal Association Between a Discrepancy Measure of Anosognosia in Patients with Dementia, Caregiver Burden and Depression Perales-Puchalt, Jaime Gascon-Bayarri, Jordi Reñé-Ramírez, Ramon Conde-Sala, JL Turró-Garriga, Oriol [Perales J] University of Kansas Medical Center, Department of Preventive Medicine and Public Health, Kansas, USA. [Turró-Garriga O] Unitat de Recerca, Hospital Santa Caterina, Institut d'Assistència Sanitària, Salt, Spain. [Gascón-Bayarri J, Reñé-Ramírez R] Unitat de Demències, Departament de Neurologia, Hospital Universitari de Bellvitge, Hospitalet de Llobregat, Spain. [Conde-Sala JL] Facultat de Psicologia, Universitat de Barcelona (UB), Barcelona, Spain Institut d'Assistència Sanitària Agnòsia Cuidadors - Estudis longitudinals HEALTH CARE::Health Care Facilities, Manpower, and Services::Health Personnel::Caregivers ANALYTICAL, DIAGNOSTIC AND THERAPEUTIC TECHNIQUES, AND EQUIPMENT::Investigative Techniques::Epidemiologic Methods::Epidemiologic Study Characteristics::Epidemiologic Studies::Cohort Studies::Longitudinal Studies DISEASES::Nervous System Diseases::Neurologic Manifestations::Neurobehavioral Manifestations::Perceptual Disorders::Agnosia ENFERMEDADES::enfermedades del sistema nervioso::manifestaciones neurológicas::manifestaciones neuroconductuales::trastornos de la percepción::agnosia ATENCIÓN DE SALUD::instalaciones, servicios y personal de asistencia sanitaria::personal sanitario::cuidadores de pacientes TÉCNICAS Y EQUIPOS ANALÍTICOS, DIAGNÓSTICOS Y TERAPÉUTICOS::técnicas de investigación::métodos epidemiológicos::características de los estudios epidemiológicos::estudios epidemiológicos::estudios de cohortes::estudios longitudinales Anosognòsia; Cuidadors; Estudis longitudinals Anosognosia; Cuidadores; Estudios longitudinales Anosognosia; Caregivers; Longitudinal studies Background: According to cross-sectional studies, there is an association between anosognosia in people with dementia and caregiver’s burden and depression. Anosognosia in patients may be a cause of caregiver burden and depression. However, variability in caregiver anosognosia ratings may exist as caregivers with burden and depression may have a more pessimistic view of the patients’ health. Objective: To assess the variability of caregiver anosognosia ratings of patients with dementia using a widely used anosognosia scale and its longitudinal relationship with caregiver burden and depression. Methods: A convenience cohort of 221 consecutive dementia outpatient and caregiver dyads was followed up at 12 and 24 months. The main instruments used were the Anosognosia Questionnaire-Dementia (AQ-D), Caregiver Burden Interview, and Geriatric Depression Scale. Linear mixed models were used including time as a factor in every model. Multivariate analyses controlled for caregiver’s socio-demographic and possible confounding factors. Results: Attrition at 12 and 24 months was 24.9% and 42.5% respectively. Patients at baseline were on average 77.8 years of age, 63.3% were women, and 63.3% had < 5 years of education. In the bivariate analyses, caregiver burden, depression, and gender were associated with caregiver ratings of total, cognitive, and personality AQ-D of the patient at different time points. Multivariate analyses revealed burden as the caregiver variable most consistently associated with total, cognitive, and personality caregiver AQ-D ratings of the patient. Conclusion: Some caregiver characteristics, especially burden, are associated with caregiver ratings of AQ-D with regard to the patient PSI 2010-19014 2021-12-09T13:21:28Z 2021-12-09T13:21:28Z 2016-08-03 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Perales J, Turró-Garriga O, Gascón-Bayarri J, Reñé-Ramírez R, Conde-Sala JL. The Longitudinal Association Between a Discrepancy Measure of Anosognosia in Patients with Dementia, Caregiver Burden and Depression. J Alzheimers Dis. 2016 Aug 3;53(3):1133-43. 1387-2877 https://hdl.handle.net/11351/6668 10.3233/JAD-160065 27258415 eng Journal of Alzheimer's Disease;53(3) https://content.iospress.com/articles/journal-of-alzheimers-disease/jad160065 Attribution-NonCommercial-NoDerivatives 4.0 International http://creativecommons.org/licenses/by-nc-nd/4.0/ info:eu-repo/semantics/openAccess application/pdf IOS Press Scientia