2026-04-13T11:55:23Zhttps://recercat.cat/oai/request

oai:recercat.cat:11351/66632025-10-24T10:32:03Zcom_2072_378070com_2072_378040col_2072_378092

Candida Periprosthetic Joint Infection: Is It Curable? Escola Verge, Laura Corona Pérez-Cardona, Pablo Salvador Pigrau Serrallach, Carles Rodríguez Pardo, Ma Dolores Candidiasi - Tractament Pròtesis - Complicacions DISEASES::Bacterial Infections and Mycoses::Mycoses::Candidiasis Other subheadings::Other subheadings::/therapy DISEASES::Bacterial Infections and Mycoses::Infection::Prosthesis-Related Infections ENFERMEDADES::infecciones bacterianas y micosis::micosis::candidiasis Otros calificadores::Otros calificadores::/terapia ENFERMEDADES::infecciones bacterianas y micosis::infección::infecciones relacionadas con prótesis Fong; Infecció articular periprotèsica; Cirurgia d'intercanvi en dues etapes Hongo; Infección de la articulación periprotésica; Cirugía de recambio en dos etapas Fungus; Periprosthetic joint infection; Two-stage exchange surgery Candida periprosthetic joint infection (CPJI) is a rare and very difficult to treat infection, and high-quality evidence regarding the best management is scarce. Candida spp. adhere to medical devices and grow forming biofilms, which contribute to the persistence and relapse of this infection. Typically, CPJI presents as a chronic infection in a patient with multiple previous surgeries and long courses of antibiotic therapy. In a retrospective series of cases, the surgical approach with higher rates of success consists of a two-stage exchange surgery, but the best antifungal treatment and duration of antifungal treatment are still unclear, and the efficacy of using an antifungal agent-loaded cement spacer is still controversial. Until more evidence is available, focusing on prevention and identifying patients at risk of CPJI seems more than reasonable. This research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors. 2025-10-24T10:32:03Z 2025-10-24T10:32:03Z 2025-10-24T10:32:03Z 2021-12-07T13:31:46Z 2021-12-07T13:31:46Z 2021-04 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion http://hdl.handle.net/11351/6663 Antibiotics;10 https://doi.org/10.3390/antibiotics10040458 Attribution 4.0 International http://creativecommons.org/licenses/by/4.0/ info:eu-repo/semantics/openAccess MDPI Scientia