2026-04-13T00:54:13Zhttps://recercat.cat/oai/requestoai:recercat.cat:11351/138752025-10-24T10:23:21Zcom_2072_378070com_2072_378040col_2072_378092
RECERCAT
author
Freixas Bermejo, Marta
author
Riera Soler, Luis
author
García Martínez, Laura
author
Segarra, Oscar
2025-10-24T10:23:21Z
2025-10-24T10:23:21Z
2025-10-16T07:23:15Z2025-10-16T07:23:15Z2025
http://hdl.handle.net/11351/13875
Crohn disease; Inflammatory bowel disease; PneumothoraxMalaltia de Crohn; Malaltia inflamatòria intestinal; PneumotòraxEnfermedad de Crohn; Enfermedad inflamatoria intestinal; NeumotóraxIntroduction: We present the case of a patient with Crohn's disease who experienced recurrent pneumothorax after starting treatment with ustekinumab.
Case presentation: A patient with Crohn's disease started an induction regimen with intravenous ustekinumab, and 2 months later he presented a left-sided pneumothorax. It had an atypical evolution that required surgical management. The medication was withdrawn and the pneumothorax resolved completely. One year later, he had a new flare-up of Crohn's disease and ustekinumab therapy was restarted, presenting a new episode of pneumothorax.
Conclusion: To our knowledge, this is the first report of recurrent pneumothorax following two separate attempts to initiate ustekinumab.
Attribution-NonCommercial 4.0 International http://creativecommons.org/licenses/by-nc/4.0/ info:eu-repo/semantics/openAccess
Crohn, Malaltia de - Tractament
Anticossos monoclonals - Ús terapèutic - Efectes secundaris
Pneumotòrax
DISEASES::Respiratory Tract Diseases::Pleural Diseases::Pneumothorax
DISEASES::Digestive System Diseases::Gastrointestinal Diseases::Gastroenteritis::Inflammatory Bowel Diseases::Crohn Disease
Other subheadings::Other subheadings::Other subheadings::/drug therapy
CHEMICALS AND DRUGS::Amino Acids, Peptides, and Proteins::Proteins::Blood Proteins::Immunoproteins::Immunoglobulins::Antibodies::Antibodies, Monoclonal
Other subheadings::Other subheadings::Other subheadings::/adverse effects
ENFERMEDADES::enfermedades respiratorias::enfermedades pleurales::neumotórax
ENFERMEDADES::enfermedades del sistema digestivo::enfermedades gastrointestinales::gastroenteritis::enfermedad inflamatoria intestinal::enfermedad de Crohn
Otros calificadores::Otros calificadores::Otros calificadores::/farmacoterapia
COMPUESTOS QUÍMICOS Y DROGAS::aminoácidos, péptidos y proteínas::proteínas::proteínas sanguíneas::inmunoproteínas::inmunoglobulinas::anticuerpos::anticuerpos monoclonales
Otros calificadores::Otros calificadores::Otros calificadores::/efectos adversos
Recurrent Pneumothorax in a Pediatric Patient with Crohn’s Disease Receiving Ustekinumab Treatment: Case Report
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion