2026-04-13T01:52:02Zhttps://recercat.cat/oai/request

oai:recercat.cat:11351/135302025-10-24T10:43:16Zcom_2072_378070com_2072_378040col_2072_378092

SEOM-GEMCAD-TTD clinical guidelines for biliary tract cancer (2025) Cano Osuna, Maria Teresa Ruiz-Casado, Ana Jiménez Gordo, Ana Maria Macarulla, Teresa Adeva, Jorge Lamarca, Angela Institut Català de la Salut [Macarulla T] Servei d’Oncologia Mèdica, Vall d’Hebron Hospital Universitari, Barcelona, Spain. [Adeva J] Medical Oncology Department, Hospital Universitario, 12 de Octubre, Madrid, Spain. [Cano Osuna MT] Medical Oncology Department, Hospital Universitario Reina Sofía, Córdoba, Spain. [Ruiz Casado A] Medical Oncology Department, Hospital Universitario Puerta de Hierro Majadahonda, Madrid, Spain. [Jiménez Gordo AM] Medical Oncology Department, Hospital Universitario Infanta Sofía, Madrid, Spain. [Lamarca A] Medical Oncology Department, Hospital Universitario Fundación Jiménez Díaz, Madrid, Spain Vall d'Hebron Barcelona Hospital Campus Tracte biliar - Càncer - Tractament Tracte biliar - Càncer - Diagnòstic DISEASES::Neoplasms::Neoplasms by Site::Digestive System Neoplasms::Biliary Tract Neoplasms Other subheadings::Other subheadings::/diagnosis HEALTH CARE::Health Services Administration::Patient Care Management::Disease Management ENFERMEDADES::neoplasias::neoplasias por localización::neoplasias del sistema digestivo::neoplasias del tracto biliar Otros calificadores::Otros calificadores::/diagnóstico ATENCIÓN DE SALUD::administración de los servicios de salud::gestión de la atención al paciente::tratamiento de las enfermedades Biliary tract cancer; Diagnosis; Precision medicine Cáncer del tracto biliar; Diagnóstico; Medicina de precisión Càncer del tracte biliar; Diagnòstic; Medicina de precisió Biliary tract cancers (BTC) are aggressive and fatal. Early recognition of symptoms and proper diagnostic work up allow for precise histopathological and molecular classification as well as accurate evaluation of the extent of disease. Surgery is the only potentially curative therapy in localized stages; however, disease recurrence is common and adjuvant chemotherapy appears to improve survival. Upfront systemic chemotherapy with immunotherapy is the treatment of choice in unresectable locally-advanced and metastatic disease. Inroads made in understanding its molecular biology has enabled new therapeutic targets to be identified with current indications and encouraging results that could further improve BTC patients' survival and quality of life. 2025-08-12T11:45:12Z 2025-08-12T11:45:12Z 2025-08 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Macarulla T, Adeva J, Cano Osuna MT, Ruiz Casado A, Jiménez Gordo AM, Lamarca A, et al. SEOM-GEMCAD-TTD clinical guidelines for biliary tract cancer (2025). Clin Transl Oncol. 2025 Aug;27:3293-306. 1699-048X http://hdl.handle.net/11351/13530 10.1007/s12094-025-03916-y 40445560 001499196300001 http://hdl.handle.net/11351/13530 eng Clinical and Translational Oncology;27 https://doi.org/10.1007/s12094-025-03916-y Attribution-NonCommercial-NoDerivatives 4.0 International http://creativecommons.org/licenses/by-nc-nd/4.0/ info:eu-repo/semantics/openAccess application/pdf Springer Scientia