2026-04-17T03:44:54Zhttps://recercat.cat/oai/requestoai:recercat.cat:11351/131442025-10-24T10:16:50Zcom_2072_378070com_2072_378040col_2072_378092
RECERCAT
author
Zhang, Yiling
author
Hensey, Owen
author
Grossberg, David
author
Tedeschi, Sara
author
Abhishek, Abhishek
author
Cai, Ken
author
Coronel, Luis
2025-10-24T10:16:50Z
2025-10-24T10:16:50Z
2025-05-26T13:03:58Z2025-05-26T13:03:58Z2025-06
http://hdl.handle.net/11351/13144
Calcium pyrophosphate deposition disease; Core domain set; DelphiEnfermedad por depósito de pirofosfato de calcio; Conjunto de dominios centrales; DelphiMalaltia per dipòsit de pirofosfat de calci; Conjunt de dominis centrals; DelphiObjective
To agree on important domains for the Outcome Measures in Rheumatology (OMERACT) core domain set for chronic and/or recurrent manifestations of calcium pyrophosphate deposition (CPPD) disease.
Methods
Patient research partners (PRPs) and other participants (mainly clinicians and researchers) contributed to three rounds of a consensus survey using Delphi methodology. Consensus was defined if ≥70% of both patients and other participants scored the domain as ‘critically important domain to include’. In a subsequent ranking exercise, all participants were asked to select and rank up to 10 of the domains reaching consensus.
Results
Fifteen domains reached consensus as critically important. Within the Pathophysiological Manifestations area, these were joint pain, joint tenderness, joint swelling, acute CPP crystal arthritis flare, joint damage on imaging tests, joint calcification on imaging tests, and crystals in joint fluid. Within the Life Impact area, these were overall function, ability to complete daily tasks, ability to work, health related quality of life, patient global assessment response to treatment, patient global assessment of disease activity, physician global assessment of disease activity, and patient satisfaction with treatment. No domains within the Societal/Resource Use area reached consensus as critically important. In the ranking exercise, joint pain, joint tenderness, joint swelling, acute CPP crystal arthritis flare and overall function were most highly ranked.
Conclusion
This work has identified potential domains for the OMERACT core domain set for chronic and/or recurrent manifestations of CPPD disease. There was strong support for joint pain, joint tenderness, joint swelling, acute CPP crystal arthritis flare, overall function, and global assessments of disease activity as core domains.
Attribution 4.0 International http://creativecommons.org/licenses/by/4.0/ info:eu-repo/semantics/openAccess
Decisió, Presa de
Dolor crònic
Condrocalcinosi
Mètode Delphi
Avaluació de resultats (Assistència sanitària)
DISEASES::Musculoskeletal Diseases::Joint Diseases::Arthritis::Chondrocalcinosis
DISEASES::Pathological Conditions, Signs and Symptoms::Pathologic Processes::Disease Attributes::Chronic Disease
PSYCHIATRY AND PSYCHOLOGY::Behavior and Behavior Mechanisms::Psychology, Social::Group Processes::Consensus
HEALTH CARE::Health Care Quality, Access, and Evaluation::Quality of Health Care::Health Care Evaluation Mechanisms::Outcome and Process Assessment (Health Care)::Outcome Assessment (Health Care)
INFORMATION SCIENCE::Information Science::Systems Analysis::Delphi Technique
ENFERMEDADES::enfermedades musculoesqueléticas::artropatías::artritis::condrocalcinosis
ENFERMEDADES::afecciones patológicas, signos y síntomas::procesos patológicos::atributos de la enfermedad::enfermedad crónica
PSIQUIATRÍA Y PSICOLOGÍA::conducta y mecanismos de la conducta::psicología social::procesos de grupo::consenso
CIENCIA DE LA INFORMACIÓN::Ciencias de la información::análisis de sistemas::técnica Delfos
ATENCIÓN DE SALUD::calidad, acceso y evaluación de la atención sanitaria::calidad de la atención sanitaria::mecanismos de evaluación de la atención sanitaria::evaluación de resultados y procesos (atención a la salud)::evaluación del desenlace (asistencia sanitaria)
Core domain set for chronic and/or recurrent manifestations of calcium pyrophosphate deposition disease: OMERACT delphi survey to establish consensus
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion