2026-04-13T02:57:10Zhttps://recercat.cat/oai/requestoai:recercat.cat:11351/124422025-10-24T10:22:24Zcom_2072_378070com_2072_378040col_2072_378092
RECERCAT
author
Forteza-Albertí, José Francisco
author
Rico, Yolanda
author
leiva, Alfonso
author
QUONIOU, Mona
author
Gual-Capllonch, Francisco
author
Rivas-Catoni, Lisandro
author
Gutierrez García-Moreno, Laura
2025-10-24T10:22:24Z
2025-10-24T10:22:24Z
2025-01-20T11:27:35Z2025-01-20T11:27:35Z2024-11-07
http://hdl.handle.net/11351/12442
Left atrial strain; Left atrial reservoir strain; Speckle tracking echocardiographyTensió auricular esquerra; Tensió del reservori auricular esquerre; Ecocardiografia de seguiment de taquesTensión auricular izquierda; Tensión del reservorio auricular izquierdo; Ecocardiografía de seguimiento de manchasBackground
Despite its proven prognostic value in different contexts, the precise implications of left atrial strain (LAS) assessment throughout different phases of the atrial cycle remain uncertain. A direct correlation between left atrial reservoir strain (LARS) and left ventricular global longitudinal strain (GLS) has been consistently demonstrated in several studies involving patients with various heart diseases. The objective of our study is to identify factors directly associated with LARS, left atrial conduction strain (LACS) and left atrial booster strain (LABS) in patients without cardiovascular (CV) disease.
Methods
Transthoracic echocardiographic examinations in patients without CV disease were prospectively selected in two tertiary hospitals echocardiography labs for clinical purposes. LAS, maximal and minimal left atrial (LA) volumes and left atrial ejection fraction (LAEF) were measured using the two-dimensional strain analysis package provided by the EchoPAC Plugging workstation (AFI LA).
Results
A total of 196 cases were included, median age of 54 (45–62) with 85 (43%) being men. The mean left ventricular ejection fraction (LVEF) was 61% ± 5, and the median GLS was − 18% (-17 to -20). Median indexed maximum volume of left atrium (LAVI) was 27 ml/m2 (22–31), and LAEF was 64% (58–70). The mean LARS biplane was 35,1% ± 8. Notably, LARS was greater in the 2-chamber view (36,1% ± 10) compared to the 4-chamber view (34,1% ± 8 p < 0,05). The multivariate analysis of LARS revealed that sex, GLS, LAEF and e’mean are independently correlated with LARS. Multivariate analysis of LACS showed independent correlations between LACS and age, GLS, LAEF, E/A ratio and e’mean. Conversely, the multivariate analysis of LABS demonstrated significant correlations among A wave, e’mean, and left atrial stiffness index (LASI).
Conclusions
In patients without CV disease, GLS emerges as a crucial determinant of LARS and LACS. LAEF and e’mean are directly and independently related to both LARS and LACS. LARS (univariate) and LACS (multivariate) exhibited a decline with older age in individuals without CV disease.
Attribution-NonCommercial-NoDerivatives 4.0 International http://creativecommons.org/licenses/by-nc-nd/4.0/ info:eu-repo/semantics/openAccess
Ecocardiografia
Sistema cardiovascular - Malalties
Cor - Ventricle esquerre - Fisiologia
PHENOMENA AND PROCESSES::Circulatory and Respiratory Physiological Phenomena::Cardiovascular Physiological Phenomena::Atrial Function::Atrial Function, Left
PHENOMENA AND PROCESSES::Circulatory and Respiratory Physiological Phenomena::Cardiovascular Physiological Phenomena::Ventricular Function::Ventricular Function, Left
ANALYTICAL, DIAGNOSTIC AND THERAPEUTIC TECHNIQUES, AND EQUIPMENT::Diagnosis::Diagnostic Techniques and Procedures::Diagnostic Imaging::Cardiac Imaging Techniques::Echocardiography
DISEASES::Cardiovascular Diseases
FENÓMENOS Y PROCESOS::fenómenos fisiológicos respiratorios y circulatorios::fenómenos fisiológicos cardiovasculares::función atrial::función del atrio izquierdo
FENÓMENOS Y PROCESOS::fenómenos fisiológicos respiratorios y circulatorios::fenómenos fisiológicos cardiovasculares::función ventricular::función ventricular izquierda
TÉCNICAS Y EQUIPOS ANALÍTICOS, DIAGNÓSTICOS Y TERAPÉUTICOS::diagnóstico::técnicas y procedimientos diagnósticos::diagnóstico por imagen::técnicas de imagen cardíaca::ecocardiografía
ENFERMEDADES::enfermedades cardiovasculares
Left atrial strain in patients without cardiovascular disease: uncovering influencing and related factors
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion