2026-04-14T02:14:00Zhttps://recercat.cat/oai/request

oai:recercat.cat:11351/121982025-10-24T10:19:15Zcom_2072_378070com_2072_378040col_2072_378092

00925njm 22002777a 4500 dc Leache, Leire author Gonzalez-Senac, Nicolas Maria author Carreras, E. author Gutiérrez-Valencia, Marta author Losa, L. author Puig, Teresa author Marrero Álvarez, Patricia author 2024-11-07T13:25:58Z 2024-11-07T13:25:58Z 2024-09-30 Aged; Inappropriate prescribing; Inpatients Ancianos; Prescripción inadecuada; Pacientes hospitalizados Persones grans; Prescripció inadequada; Pacients hospitalitzats Purpose In recent years, the need for a more appropriate prescription of medications in the older population has emerged as a significant public health concern. In this study, we aimed to evaluate the prevalence of potentially inappropriate medications (PIM) in hospitalized adults aged ≥ 75. Patients and methods This was a retrospective descriptive observational study of patients at 16 hospitals in Spain. The study population included inpatients aged ≥ 75 admitted during a 7-day period (May 10 to 16, 2021). Data were obtained from the pharmacy databases of the participating hospitals. The list of PIMs was based on the Beers, STOPP-START, EU-PIM and PRISCUS criteria. Results A total of 4,183 patients were included. PIMs were detected in 23.5% (N = 1,126) of the cohort. The prevalence rates at the participating hospitals ranged from 10% to 42.5%. The PIM/patient ratio was 1.2. The most common PIMs were midazolam, dexketoprofen, diazepam, and doxazosin, all of which (except for doxazosin) were more common in women. Benzodiazepines accounted for 70% of all PIMs. In 35% of cases, the PIMs were initiated before hospital admission. Of the 818 PIMs initiated during hospitalization, the two most common were benzodiazepines (49%) and anti-inflammatory drugs (25%). At discharge, only 4.9% of the PIMs initiated during the hospital stay were still prescribed. Conclusion In this population of older hospitalized patients, the overall prevalence of PIMs was moderate. However, the prevalence rate at the participating hospitals was highly variable. In most cases, PIMs prescribed prior to hospitalization for chronic conditions were not withdrawn during the hospital stay. No significant increase in PIMs was observed from pre-admission to post-discharge. These findings underscore the need for multidisciplinary interventions to optimize the pharmaceutical treatment in older adults in the hospital setting to reduce the consequences of PIMs in patients. http://hdl.handle.net/11351/12198 Persones grans Errors de medicació Hospitals - Pacients NAMED GROUPS::Persons::Age Groups::Adult::Aged HEALTH CARE::Health Services Administration::Quality of Health Care::Quality Assurance, Health Care::Potentially Inappropriate Medication List HEALTH CARE::Health Care Facilities, Manpower, and Services::Health Services::Medical Errors::Medication Errors::Inappropriate Prescribing HEALTH CARE::Health Care Facilities, Manpower, and Services::Health Services::Patient Care::Hospitalization DENOMINACIONES DE GRUPOS::personas::Grupos de Edad::adulto::anciano ATENCIÓN DE SALUD::administración de los servicios de salud::calidad de la atención sanitaria::garantía de calidad de la atención sanitaria::Lista de medicamentos potencialmente inadecuados ATENCIÓN DE SALUD::instalaciones, servicios y personal de asistencia sanitaria::servicios de salud::errores médicos::errores de medicación::prescripción inadecuada ATENCIÓN DE SALUD::instalaciones, servicios y personal de asistencia sanitaria::servicios de salud::asistencia al paciente::hospitalización Prevalence of potentially inappropriate medications and prescription dynamics in elderly hospitalized patients in Spain