2026-04-17T13:53:13Zhttps://recercat.cat/oai/request

oai:recercat.cat:11351/116562025-10-24T10:40:33Zcom_2072_378070com_2072_378040col_2072_378092

00925njm 22002777a 4500 dc Muñoz-Rodriguez, Jesus author Paesano, Nahuel author Picola Brau, Natalia author Ruiz Plazas, Xavier author Celma, Ana author Muñoz Rivero, Marta Viridiana author Morote Robles, Juan author 2024-07-02T10:06:20Z 2024-07-02T10:06:20Z 2024-08 Prostate cancer; Early detection; Predictive models Càncer de pròstata; Detecció precoç; Models predictius Cáncer de próstata; Detección precoz; Modelos predictivos Quality control of programs for detection of significant prostate cancer (sPCa) could be defined by the correlation between observed and reference 95% confidence intervals (CIs) for Prostate Imaging-Reporting and Data System (PI-RADS) categories. We used the area under the receiver operating characteristic curve (AUC) for the Barcelona magnetic resonance imaging (MRI) predictive model to screen the quality of ten participant centers in the sPCa opportunistic early detection program in Catalonia. We set an AUC of <0.8 as the criterion for suboptimal quality. Quality was confirmed in terms of the correlation between actual sPCa detection rates and reference 95% CIs. For a cohort of 2624 men with prostate-specific antigen >3.0 ng/ml and/or a suspicious digital rectal examination who underwent multiparametric MRI and two- to four-core targeted biopsies of PI-RADS ≥3 lesions and/or 12-core systematic biopsy, AUC values ranged from 0.527 to 0.914 and were <0.8 in four centers (40%). There was concordance between actual sPCa detection rates and reference 95% CIs for one or two PI-RADS categories when the AUC was <0.8, and for three or four PI-RADS categories when the AUC was ≥0.8. A review of procedures used for sPCa detection should be recommended in centers with suboptimal quality. Patient summary We tested a method for assessing quality control for centers carrying out screening for early detection of prostate cancer. We found that the method can identify centers that may need to review their procedures for detection of significant prostate cancer. http://hdl.handle.net/11351/11656 Càncer - Detecció precoç Pròstata - Càncer - Diagnòstic Control de qualitat ANALYTICAL, DIAGNOSTIC AND THERAPEUTIC TECHNIQUES, AND EQUIPMENT::Diagnosis::Early Diagnosis::Early Detection of Cancer DISEASES::Neoplasms::Neoplasms by Site::Urogenital Neoplasms::Genital Neoplasms, Male::Prostatic Neoplasms PUBLIC HEALTH::Environmental Health::General Aspects::Control::Quality Control TÉCNICAS Y EQUIPOS ANALÍTICOS, DIAGNÓSTICOS Y TERAPÉUTICOS::diagnóstico::diagnóstico precoz::detección precoz del cáncer ENFERMEDADES::neoplasias::neoplasias por localización::neoplasias urogenitales::neoplasias de los genitales masculinos::neoplasias de la próstata SALUD PÚBLICA::salud ambiental::aspectos generales::control::control de calidad Evaluating the Quality of Local Programs for Early Detection of Significant Prostate Cancer