2026-04-13T03:09:56Zhttps://recercat.cat/oai/request

oai:recercat.cat:11351/116512025-10-24T10:21:40Zcom_2072_378070com_2072_378040col_2072_378092

Risk Factors Associated with Loss to Follow-Up during Tuberculosis Treatment in the Sanatorium Hospital of Luanda, Angola Vita, Domingos Kansietoko, Debora Cristina Maindo Sebastiao Aznar, María Luisa Martínez-Campreciós, Joan Molina Romero, Israel Tuberculosi - Angola Tuberculosi - Factors de risc Tuberculosi - Tractament GEOGRAPHICALS::Geographic Locations::Africa::Africa South of the Sahara::Africa, Southern::Angola ANALYTICAL, DIAGNOSTIC AND THERAPEUTIC TECHNIQUES, AND EQUIPMENT::Investigative Techniques::Epidemiologic Methods::Statistics as Topic::Probability::Risk::Risk Factors PUBLIC HEALTH::Environmental Health::Health::Environmental Illness::Communicable Diseases::Tuberculosis Other subheadings::Other subheadings::Other subheadings::/drug therapy DENOMINACIONES GEOGRÁFICAS::localizaciones geográficas::África::África subsahariana::África del Sur::Angola TÉCNICAS Y EQUIPOS ANALÍTICOS, DIAGNÓSTICOS Y TERAPÉUTICOS::técnicas de investigación::métodos epidemiológicos::estadística como asunto::probabilidad::riesgo::factores de riesgo SALUD PÚBLICA::salud ambiental::salud::enfermedad ambiental::enfermedades transmisibles::tuberculosis Otros calificadores::Otros calificadores::Otros calificadores::/farmacoterapia Food insecurity; Loss to follow-up; Tuberculosis Inseguretat alimentària; Pèrdua de seguiment; Tuberculosi Inseguridad alimentaria; Pérdida de seguimiento; Tuberculosis Background: Tuberculosis (TB) continues to be a serious public health threat that affects the most vulnerable populations. Patients who are lost to follow-up (LTFU) after TB diagnosis still represent one of the biggest challenges to TB control. Method: In this prospective observational study, we aimed to identify and analyse the risk factors associated with LTFU among TB patients who started first-line TB treatment in the Sanatorium Hospital in Luanda. Result: A total of 113 patients with TB (non-multidrug resistant) were included between August 2018 and September 2019. Seventy-six (67.3%) patients were cured, 27 (23.9%) were LTFU, 5 (4.4%) died, 4 (3.5%) were transferred and 1 (0.9%) presented treatment failure. After excluding those who died, were transferred or failed treatment, we observed that severe TB at the time of diagnosis (OR 9.24, 95% CI 2.18-39.04) and food insecurity were significantly associated with LTFU (OR 5.96, 95% CI 1.66-21.41). Conclusions: The findings of our study can contribute to understanding the reasons for the LTFU of patients with TB and can guide policies and facilitate designing measures to allow better adherence and, therefore, greater treatment success. 2025-10-24T10:21:40Z 2025-10-24T10:21:40Z 2025-10-24T10:21:40Z 2024-07-01T11:41:52Z 2024-07-01T11:41:52Z 2024-06-12 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion http://hdl.handle.net/11351/11651 Tropical Medicine and Infectious Disease;9(6) https://doi.org/10.3390/tropicalmed9060131 Attribution 4.0 International http://creativecommons.org/licenses/by/4.0/ info:eu-repo/semantics/openAccess MDPI Scientia