2026-04-17T11:42:18Zhttps://recercat.cat/oai/request

oai:recercat.cat:11351/115342025-06-24T00:12:03Zcom_2072_378071com_2072_378040col_2072_378097

00925njm 22002777a 4500 dc Brik, Maia author Gil Cuevas, Judit author Mota Foix, Miriam author Barranco, Francisco José author Garcia-Ruiz, Itziar author SANDONIS, MIGUEL ANGEL author Hernandez Fleury, Alina author Maiz, Nerea author Carreras, Elena author 2024-05-31T11:03:27Z 2024-05-31T11:03:27Z 2024-06 Cannabis; Fetal growth; Preterm birth Canabis; Crecimiento fetal; Parto prematuro Cannabis; Creixement fetal; Part prematur Introduction Cannabis potency and its use during pregnancy have increased in the last decade. The aim of this study was to investigate the impact of antenatal cannabis use on fetal growth, preterm birth and other perinatal outcomes. Material and methods A propensity score-matched analysis was performed in women with singleton pregnancies attending a tertiary care site in Barcelona. Women in the cannabis group were selected based on the results of a detection test. Primary outcomes were small for gestational age at birth (SGA), low birthweight and preterm birth. Secondary outcomes were other biometric parameters (neonatal length and head circumference), respiratory distress, admission to the neonatal intensive care unit and breastfeeding at discharge. A second propensity score-matched analysis excluding other confounders (use of other recreational drugs and discontinuation of cannabis use during pregnancy) was performed. Results Antenatal cannabis was associated with a higher odds ratio of SGA (OR 3.60, 95% CI: 1.68–7.69), low birthweight (OR 3.94, 95% CI: 2.17–7.13), preterm birth at 37 weeks (OR 2.07, 95% CI: 1.12–3.84) and 32 weeks of gestation (OR 4.13, 95% CI: 1.06–16.11), admission to the neonatal intensive care unit (OR 1.95, 95% CI: 1.03–3.71), respiratory distress (OR 2.77, 95% CI: 1.26–6.34), and lower breastfeeding rates at discharge (OR 0.10, 95% CI: 0.05–0.18). When excluding other confounders, no significant association between antenatal cannabis use and SGA was found. Conclusions Antenatal cannabis use increases the risk of SGA, low birthweight, preterm birth and other adverse perinatal outcomes. However, when isolating the impact of cannabis use by excluding women who use other recreational drugs and those who discontinue cannabis during pregnancy, no significant association between antenatal cannabis use and SGA birth was found. This research was funded by the Maternal and Fetal Medicine Research Group of Vall d'Hebron Research Institute (VHIR). Cànnabis Maltractament prenatal per abús de substàncies Infants prematurs Avaluació de resultats (Assistència sanitària) Embaràs - Complicacions ORGANISMS::Eukaryota::Plants::Viridiplantae::Streptophyta::Embryophyta::Tracheophyta::Magnoliopsida::Rosanae::Rosales::Cannabaceae::Cannabis Other subheadings::Other subheadings::Other subheadings::/adverse effects NAMED GROUPS::Persons::Age Groups::Infant::Infant, Newborn::Infant, Low Birth Weight::Infant, Small for Gestational Age DISEASES::Female Urogenital Diseases and Pregnancy Complications::Pregnancy Complications::Obstetric Labor Complications::Obstetric Labor, Premature::Premature Birth ANALYTICAL, DIAGNOSTIC AND THERAPEUTIC TECHNIQUES, AND EQUIPMENT::Diagnosis::Prognosis::Pregnancy Outcome ORGANISMOS::Eukaryota::plantas::Viridiplantae::Streptophyta::Embryophyta::Tracheophyta::Magnoliopsida::Rosanae::Rosales::Cannabaceae::Cannabis Otros calificadores::Otros calificadores::Otros calificadores::/efectos adversos DENOMINACIONES DE GRUPOS::personas::Grupos de Edad::lactante::recién nacido::recién nacido de bajo peso::recién nacido pequeño para su edad gestacional ENFERMEDADES::enfermedades de los genitales femeninos y complicaciones del embarazo::complicaciones del embarazo::complicaciones del parto::parto prematuro::nacimiento prematuro TÉCNICAS Y EQUIPOS ANALÍTICOS, DIAGNÓSTICOS Y TERAPÉUTICOS::diagnóstico::pronóstico::resultado del embarazo Cannabis exposure during pregnancy and perinatal outcomes: A cohort study