2026-04-13T07:33:34Zhttps://recercat.cat/oai/request

oai:recercat.cat:11351/114142024-11-01T03:01:40Zcom_2072_451665com_2072_378040com_2072_378071col_2072_451666col_2072_378097

Cognitive Profile and Cardiovascular Risk Factors in Older Adults with Mild Cognitive Impairment Vázquez De Sebastián, Julia Ortiz Zúñiga, Ángel Michael Ciudin Mihai, Andreea Ars , Joan Inzitari, Marco Simó Canonge, Rafael Ariño-Blasco, Sergio Torres-Pascual, Cristina Castellano-Tejedor, Carmina Diabetis no-insulinodependent Cor - Malalties - Factors de risc Deteriorament cognitiu lleu DISEASES::Cardiovascular Diseases DISEASES::Nutritional and Metabolic Diseases::Metabolic Diseases::Glucose Metabolism Disorders::Diabetes Mellitus::Diabetes Mellitus, Type 2 PSYCHIATRY AND PSYCHOLOGY::Mental Disorders::Neurocognitive Disorders::Cognition Disorders::Cognitive Dysfunction ANALYTICAL, DIAGNOSTIC AND THERAPEUTIC TECHNIQUES, AND EQUIPMENT::Investigative Techniques::Epidemiologic Methods::Statistics as Topic::Probability::Risk::Risk Factors ENFERMEDADES::enfermedades cardiovasculares ENFERMEDADES::enfermedades nutricionales y metabólicas::enfermedades metabólicas::trastornos del metabolismo de la glucosa::diabetes mellitus::diabetes mellitus tipo II PSIQUIATRÍA Y PSICOLOGÍA::trastornos mentales::trastornos neurocognitivos::trastornos cognitivos::disfunción cognitiva TÉCNICAS Y EQUIPOS ANALÍTICOS, DIAGNÓSTICOS Y TERAPÉUTICOS::técnicas de investigación::métodos epidemiológicos::estadística como asunto::probabilidad::riesgo::factores de riesgo Cardiovascular risk factors; Cognitive impairment; Type 2 diabetes Factors de risc cardiovascular; Discapacitat cognitiva; Diabetis tipus 2 Factores de riesgo cardiovascular; Discapacidad cognitiva; Diabetis tipo 2 The prevalence of cardiovascular risk factors (CVRFs) in the older adults population and their specific impact on their cognitive profiles still requires further research. For this purpose, a cross-sectional study was carried out to describe the presence of CVRFs and their association with cognitive performance in a sample of older adults (65–85 years old) with Mild Cognitive Impairment (MCI). Participants (n = 185) were divided into three groups concerning their cardiovascular risk level determined by the presence of different CVRFs, including Type 2 Diabetes (T2D), dyslipidemia, hypertension, and obesity. The primary outcome measures were the participant’s scores in the Repeatable Battery for the Assessment of Neuropsychological Status (RBANS). Sociodemographic, clinical, and psychosocial data were collected. Non-parametrical statistical analyses and effect sizes were calculated. Findings revealed that a greater presence of CVRFs was not associated with a worse overall cognitive performance. High-risk patients were more likely to have significantly worse performance in the attentional domain compared to medium-risk (p = 0.029, r = 0.42) and compared to low-risk (p = 0.041, r = 0.35), specifically in the digits repetition subtest (p = 0.042). T2D alone was the CVRF associated with cognitive differences (p = 0.037, r = 0.32), possibly mediated by the duration of the condition. Consequently, a higher presence of CVRFs did not lead to a worse overall cognitive performance. However, high-risk individuals were more likely to experience cognitive impairment, particularly in the attentional domain. T2D played a significant role in these cognitive profile differences, possibly influenced by its duration. This research has been financed by the European Union through the European Regional Development Fund (ERDF). Fons Europeu de Desenvolupament Regional (FEDER) & ACCIÓ for DIALCAT research (ref.: COMRDI B64574221423350). 2024-05-06T09:51:58Z 2024-05-06T09:51:58Z 2024-04-18 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion International Journal of Environmental Research and Public Health;21(4) https://doi.org/10.3390/ijerph21040500 Attribution 4.0 International http://creativecommons.org/licenses/by/4.0/ info:eu-repo/semantics/openAccess MDPI Scientia