2026-04-13T07:08:35Zhttps://recercat.cat/oai/request

oai:recercat.cat:11351/112152025-10-24T10:56:06Zcom_2072_451667com_2072_378040col_2072_451668

The impact of volume overload on technique failure in incident peritoneal dialysis patients Vrtovsnik, Francois VERGER, Christian Van Biesen, Wim Fan, Stanley SHIN, SUG KYUN Rodríguez, Carmen Garcia Méndez, Isabel Diàlisi peritoneal Hemodiàlisi ANALYTICAL, DIAGNOSTIC AND THERAPEUTIC TECHNIQUES, AND EQUIPMENT::Therapeutics::Renal Replacement Therapy::Renal Dialysis::Peritoneal Dialysis ANALYTICAL, DIAGNOSTIC AND THERAPEUTIC TECHNIQUES, AND EQUIPMENT::Investigative Techniques::Epidemiologic Methods::Epidemiologic Study Characteristics::Epidemiologic Studies::Cohort Studies TÉCNICAS Y EQUIPOS ANALÍTICOS, DIAGNÓSTICOS Y TERAPÉUTICOS::terapéutica::tratamiento de reemplazo renal::diálisis renal::diálisis peritoneal CARACTERÍSTICAS DE PUBLICACIONES::características del estudio::estudio clínico::estudio observacional Diàlisi peritoneal; Hemodiàlisi; Estudi observacional Diálisis peritoneal; Hemodiálisis; Estudio observacional Peritoneal Dialysis; Hemodialysis; Cohort study Background: Technique failure in peritoneal dialysis (PD) can be due to patient- and procedure-related factors. With this analysis, we investigated the association of volume overload at the start and during the early phase of PD and technique failure. Methods: In this observational, international cohort study with longitudinal follow-up of incident PD patients, technique failure was defined as either transfer to haemodialysis or death, and transplantation was considered as a competing risk. We explored parameters at baseline or within the first 6 months and the association with technique failure between 6 and 18 months, using a competing risk model. Results: Out of 1092 patients of the complete cohort, 719 met specific inclusion and exclusion criteria for this analysis. Being volume overloaded, either at baseline or Month 6, or at both time points, was associated with an increased risk of technique failure compared with the patient group that was euvolaemic at both time points. Undergoing treatment at a centre with a high proportion of PD patients was associated with a lower risk of technique failure. Conclusions: Volume overload at start of PD and/or at 6 months was associated with a higher risk of technique failure in the subsequent year. The risk was modified by centre characteristics, which varied among regions. The study has been funded by Fresenius Medical Care Deutschland GmbH and Fresenius Medical Care Asia Pacific Ltd. 2025-10-24T10:56:05Z 2025-10-24T10:56:05Z 2025-10-24T10:56:05Z 2024-03-20T09:59:35Z 2024-03-20T09:59:35Z 2019-12-22 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion http://hdl.handle.net/11351/11215 Clinical Kidney Journal;14(2) https://doi.org/10.1093/ckj/sfz175 Attribution-NonCommercial 4.0 International http://creativecommons.org/licenses/by-nc/4.0/ info:eu-repo/semantics/openAccess Oxford University Press Scientia